Thermo Scientific Chemicals

Trichloromethyl chloroformate, 98%, Thermo Scientific Chemicals

Catalog number: A17444.30
250 g, Each
Thermo Scientific Chemicals

Trichloromethyl chloroformate, 98%, Thermo Scientific Chemicals

Catalog number: A17444.30
250 g, Each
Quantity
Catalog number: A17444.30
also known as A17444-30
Price (TWD)

Chemical Identifiers

CAS
503-38-8
IUPAC Name
trichloromethyl carbonochloridate
Molecular Formula
C2Cl4O2
InChI Key
HCUYBXPSSCRKRF-UHFFFAOYSA-N
SMILES
ClC(=O)OC(Cl)(Cl)Cl
Appearance (Color)
Clear colorless
Assay (Titration ex Chloride)
≥97.5 to ≤102.5%
Refractive Index
1.4560-1.4600 @ 20?C
Identification (FTIR)
Conforms
Form
Liquid

Description

Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.

Solubility
Miscible with ethanol, ether and benzene. Immiscible with water.

Notes
Special handling precautions required. View MSDS prior to purchase. MSDS are available online at www.alfa.comStore in a cool place. Light and heat sensitive. Incompatible with strong oxidizing agents and bases.
RUO – Research Use Only

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