Thermo Scientific Chemicals

Trimethylsilyl cyanide, 97%, Thermo Scientific Chemicals

Catalog number: A19598.22
100 g, Each
Thermo Scientific Chemicals

Trimethylsilyl cyanide, 97%, Thermo Scientific Chemicals

Catalog number: A19598.22
100 g, Each
Quantity
Catalog number: A19598.22
also known as A19598-22
Price (TWD)

Chemical Identifiers

CAS
7677-24-9
IUPAC Name
trimethylsilanecarbonitrile
Molecular Formula
C4H9NSi
InChI Key
LEIMLDGFXIOXMT-UHFFFAOYSA-N
SMILES
C[Si](C)(C)C#N
Assay (GC)
≥96.0% (non-U.S. sourced material)
Form
Liquid
Comment
Material sourced in the U.S. and in other countries
Appearance (Color)
Clear, colorless to yellow
Assay from Supplier's CofA
≥96.0% (U.S. sourced material)

Description

Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.

Solubility
Miscible with organic solvents.

Notes
Moisture sensitive. Store in a cool place.Incompatible with water, strong oxidizing agents, strong reducing agents, strong acids and strong bases.
RUO – Research Use Only

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