MSTFA and MSTFA + 1% TMCS Silylation Reagent
MSTFA and MSTFA + 1% TMCS Silylation Reagent
Actual product may vary
Thermo Scientific™

MSTFA and MSTFA + 1% TMCS Silylation Reagent

Offer maximum volatility with the Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent.

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Catalog NumberStandard ComponentsQuantity
TS-48915MSTFA plus 1% TMCS (2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)-acetamide, Chlorotrimethylsilane)10 x 1 mL ampules
TS-48911MSTFA (N-Methyl-N-trimethylsilyltrifluoroacetamide)10 g
TS-48910MSTFA (N-Methyl-N-trimethylsilyltrifluoroacetamide)10 x 1 mL ampules
TS-48914MSTFA (N-Methyl-N-trimethylsilyltrifluoroacetamide)100 mL
TS-48913MSTFA (N-Methyl-N-trimethylsilyltrifluoroacetamide)25 mL
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Catalog number TS-48915
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Standard Components:
MSTFA plus 1% TMCS (2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)-acetamide, Chlorotrimethylsilane)
Quantity:
10 x 1 mL ampules

Use Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent for GC analyses of early eluting compounds that would otherwise be obscured in the chromatogram. MSTFA, the most volatile TMS-amide available, and its byproduct N-methyltrifluoroacetamide typically elute with the solvent front, allowing TMS derivatives of small molecules to be analyzed. Addition of Thermo Scientific™ TMCS aids derivatization of amides, secondary amines, and hindered hydroxyls not derivatized by MSTFA alone.

  • Trimethylsilyl donor strength comparable to BSA and BSTFA
  • Reacts to replace labile hydrogens on a wide range of polar compounds with a Si(CH3)3 group
  • Used to prepare volatile and thermally stable derivatives for GC and MS
  • Volatile byproduct, N-methyltrifluoroacetamide, has an even lower retention time than MSTFA
  • Often TMS derivatives of small molecules can be analyzed when derivatized with MSTFA because the byproducts and the reagent itself usually elute with the solvent front
  • Addition of Thermo Scientfic TMCS aids derivatization of amides, secondary amines and hindered hydroxyls not derivatized by MSTFA alone
For Research Use Only. Not for use in diagnostic procedures.
Specifications
For Use WithGC/MS
Standard Concentration98 to 100, 0.1 to 1%
HazardsFlammable, Irritant
Storage2°C to 8°C
Quantity10 x 1 mL ampules
Standard ComponentsMSTFA plus 1% TMCS (2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)-acetamide, Chlorotrimethylsilane)
Unit SizeEach