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結構搜尋Thermo Scientific Chemicals
4-Epitetracycline hydrochloride, can be used as a secondary standard
產品號碼: 233121000
100mg, Glass bottle, Each
化學識別
CAS
23313-80-6
IUPAC Name
hydrogen (2Z,4R,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione chloride
Molecular Formula
C22H25ClN2O8
InChI Key
DYQBMRZOOXYHIM-JOUMVXTGSA-N
SMILES
[H+].[Cl-].CN(C)[C@@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O
規格
規格表Appearance (Color)
Yellow
Appearance (Form)
Crystalline powder
Purity
>=80 % (as is, calculated)
Infrared spectrum
Conforms
說明
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- 4-Epitetracycline hydrochloride is a metabolite derived from the degradation of tetracycline compounds and has been shown to display antibiotic activity
- This compound blocks protein synthesis by binding to the 30S ribosomal subunit and interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex
Applications
- This semi-synthesized compound derived from actinomycetes can decrease the activity of the Tet repressor effector in animal models
- In vivo experiments revealed that 4-epitetracycline hydrochloride can induce a toxic response
RUO – Research Use Only
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