2-(Trifluoromethyl)benzaldehyde, 98%, Thermo Scientific Chemicals
2-(Trifluoromethyl)benzaldehyde, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

2-(Trifluoromethyl)benzaldehyde, 98%, Thermo Scientific Chemicals

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產品號碼 B24591.06
亦稱為 B24591-06
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化學識別
CAS447-61-0
IUPAC Name2-(trifluoromethyl)benzaldehyde
Molecular FormulaC8H5F3O
InChI KeyZDVRPKUWYQVVDX-UHFFFAOYSA-N
SMILESFC(F)(F)C1=CC=CC=C1C=O
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規格Specification Sheet規格表
Appearance (Color)Clear colorless to pale yellow
FormLiquid
Assay (GC)≥97.5%
Identification (FTIR)Conforms
Refractive Index1.4640-1.4680 @ 20°C
2-(Trifluoromethyl)benzaldehyde has been used in the preparation of ω-(dimethylamino)-alkylethyl-4(-2-(trifluorormethyl)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates, methyl (E)-2-[2-[(E)-2-(2-trifluoromethylphenyl)vinyl]-phenyl]-3-methoxyacrylate via Wittig-Horner reaction. It is a reagent used as electrophilic component in a wide array of reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-(Trifluoromethyl)benzaldehyde has been used in the preparation of ω-(dimethylamino)-alkylethyl-4(-2-(trifluorormethyl)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates, methyl (E)-2-[2-[(E)-2-(2-trifluoromethylphenyl)vinyl]-phenyl]-3-methoxyacrylate via Wittig-Horner reaction. It is a reagent used as electrophilic component in a wide array of reactions.

Solubility
Soluble in most organic solvents.

Notes
Air sensitive. Store under dry inert gas. Store away from oxidizing agents, air.
RUO – Research Use Only

General References:

  1. N Baindur; A Rutledge; D J Triggle. A homologous series of permanently charged 1,4-dihydropyridines: novel probes designed to localize drug binding sites on ion channels. Journal of Medicinal Chemistry. 1993, 36 (23), 3743-3745.
  2. J Alzeer, J Chollet; I Heinze-Krauss; C Hubschwerlen; H Matile; R G Ridley. Phenyl beta-methoxyacrylates: a new antimalarial pharmacophore. Journal of Medicinal Chemistry. 2000, 43 (4), 560-568.