Thermo Scientific Chemicals

Difluoromethyl phenyl sulfone, 95%, Thermo Scientific Chemicals

產品號碼: H64760.06
5 g, Each
Thermo Scientific Chemicals

Difluoromethyl phenyl sulfone, 95%, Thermo Scientific Chemicals

產品號碼: H64760.06
5 g, Each
Quantity
產品號碼: H64760.06
亦稱為 H64760-06
價格 (TWD)

化學識別

CAS
1535-65-5
IUPAC Name
difluoromethanesulfonylbenzene
Molecular Formula
C7H6F2O2S
InChI Key
LRHDNAVPELLXDL-UHFFFAOYSA-N
SMILES
FC(F)S(=O)(=O)C1=CC=CC=C1
Assay (HPLC)
>94.0%

說明

Used as a reagent for the nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls and fluorination. Reagent used for reductive silylation and the preparation of trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes, fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors, difluoromethylation of primary alkyl halides via nucleophilic substitution-reductive desulfonylation. Also used as reagent in preparation of α-difluoromethyl amines via stereo selective (phenylsulfonyl)difluoromethylation of chiral sulfinyl aldimines and Anti-difluoropropanediols via potassium tert-butoxide-catalyzed difluoromethylenation of aldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used as a reagent for the nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls and fluorination. Reagent used for reductive silylation and the preparation of trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes, fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors, difluoromethylation of primary alkyl halides via nucleophilic substitution-reductive desulfonylation. Also used as reagent in preparation of α-difluoromethyl amines via stereo selective (phenylsulfonyl)difluoromethylation of chiral sulfinyl aldimines and Anti-difluoropropanediols via potassium tert-butoxide-catalyzed difluoromethylenation of aldehydes.

Solubility
Soluble in chloroform and water.

Notes
Keep container tightly closed. With adequate ventilation. Store away from oxidizing agent.
RUO – Research Use Only

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