Applications
PIPES can be used in a wide array of biological applications, including as a component in media formulations. Specific applications include buffers for cell culture and diagnostic reagent production. It is used to buffer glutaraldehyde fixative solutions when fixing plant and/or animal tissue tissue samples. This will help prevent the loss of lipids. It is used to buffer glutaraldehyde and formaldehyde when fixing fungal zoospores for fluorescence microscopy and electron microscopy.

Solubility
Fully miscible in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents, reducing agents, bases and heat.