Citraconic anhydride is used as a monomer for specialty unsaturated polyester resins. It is used to prepare bicyclic pyrrolidines, maleimides and co- and terpolymers. It is also used for the protection of N-terminal amino acids. Further, it is involved in the preparation of clothing ping acid and its amide. In addition to this, it is selectively used for the isolation of histidyl peptides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Citraconic anhydride is used as a monomer for specialty unsaturated polyester resins. It is used to prepare bicyclic pyrrolidines, maleimides and co- and terpolymers. It is also used for the protection of N-terminal amino acids. Further, it is involved in the preparation of clothing ping acid and its amide. In addition to this, it is selectively used for the isolation of histidyl peptides.
Solubility
Miscible with water, alcohol, acetone and ether.
Notes
Moisture sensitive. Incompatible with bases, oxidizing agents and reducing agents.
RUO – Research Use Only
General References:
- Reagent for the protection of amino groups: Biochem. J., 109, 312 (1968).
- Wang, L.; Wang, H.; Li, Y.; Tang, P. Total Synthesis of Schilancitrilactones B and C. Angew. Chem. Int. Ed. 2015, 54 (19), 5732-5735.
- Eddy, N. A.; Fenteany, G. Model studies directed to the synthesis of cucurbitacin I C/D rings. Tetrahedron Lett. 2015, 56 (36), 5079-5081.