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LOADING
See other CASP8 SIRNA Assays ›
Gene Symbol:
CASP8
Gene Name:
caspase 8
Gene Aliases:
ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
Chromosome Location:
Chr.2: 201233443 - 201287711 on Build GRCh38
UniGene ID:
Hs.599762
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID
s2427
Validated
Purification
HPLC
Standard
HPLC-IVR
Size
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
1 umol
10 umol
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
1 umol
10 umol
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
1 umol
10 umol
Availability
Inventoried
Catalog #
4390824
Price
Your Price
Online offer:
Check your price ›
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Genomic Map
siRNA Details
More Information
Genomic Map
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siRNA Details
Gene Symbol: CASP8
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_001080124.1
NP_001073593.1
7
899
NM_001080125.1
NP_001073594.1
7
1087
NM_001228.4
NP_001219.2
8
1063
NM_033355.3
NP_203519.1
8
918
NM_033356.3
NP_203520.1
6
804
NM_033358.3
NP_203522.1
7
947
NR_111983.1
7
1087
XM_005246885.1
XP_005246942.1
6
862
XM_005246886.1
XP_005246943.1
7
833
XM_005246887.1
XP_005246944.1
8
985
XM_005246888.1
XP_005246945.1
8
927
XM_005246889.1
XP_005246946.1
7
804
XM_005246890.3
XP_005246947.1
7
811
XM_005246891.4
XP_005246948.1
7
1051
XM_005246892.1
XP_005246949.1
6
759
XM_005246893.2
XP_005246950.1
6
842
XM_005246894.3
XP_005246951.1
7
917
XM_005246895.2
XP_005246952.1
5
797
XM_006712789.1
XP_006712852.1
8
944
XM_006712790.3
XP_006712853.1
7
823
XM_006712793.2
XP_006712856.1
7
920
XM_011511969.1
XP_011510271.1
5
388
GenBank mRNA
AB451282.1
-
5
664
AB451414.1
-
5
664
AF009620.1
-
5
664
AF380342.1
-
7
794
AF422927.1
-
7
887
AF422928.1
-
8
906
BC028223.2
-
6
736
BC068050.1
-
6
754
6421760
BX395849.2
-
6
753
JN657192.1
-
4
560
U58143.1
-
6
709
U60520.1
-
8
1016
X98172.1
-
7
1000
X98173.1
-
6
736
X98175.1
-
3
214
X98176.1
-
7
833
X98177.1
-
6
709
X98178.1
-
5
664
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More Information
Other Species Targeted
This siRNA also targets the following transcripts in Mouse: NM_009812, NM_001080126, NM_001277926, AK146758, AK168812, and others.
Matching Taqman Gene Expression Assay:
Hs00236278_m1
Panther Classification:
Molecular Function -
protease
Gene Ontology Categories:
Function(s)
Process(es)
proteolysis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular component disassembly involved in execution phase of apoptosis
cell surface receptor signaling pathway
response to cold
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
natural killer cell activation
macrophage differentiation
response to cobalt ion
response to estradiol
response to lipopolysaccharide
response to tumor necrosis factor
TRIF-dependent toll-like receptor signaling pathway
TRAIL-activated apoptotic signaling pathway
suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process
T cell activation
B cell activation
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to ethanol
positive regulation of macrophage differentiation
positive regulation of proteolysis
response to antibiotic
protein heterooligomerization
proteolysis involved in cellular protein catabolic process
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
nucleotide-binding oligomerization domain containing signaling pathway
cellular response to mechanical stimulus
cellular response to organic cyclic compound
death-inducing signaling complex assembly
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
execution phase of apoptosis
activation of cysteine-type endopeptidase activity
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
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