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Invitrogen
Human ANKH (aa 448-492) Control Fragment Recombinant Protein
Product Details
RP-107620
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
ACYVYRKQKKKMENESATEGEDSAMTDMPPTEEVTDIVEMREENE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Unconjugated
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66977. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANK; ankylosis, progressive homolog; ATP carrier protein ANKH; FLJ27166; Mineralization regulator ANKH; Progressive ankylosis protein homolog
Gene Aliases: ANK; ANKH; CCAL2; CMDJ; CPPDD; HANK; KIAA1581; MANK; UNQ241/PRO274
UniProt ID: (Human) Q9HCJ1
Entrez Gene ID: (Human) 56172
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