Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 14 amino acids near the amino terminus of human APC4
PEP-1059 can be used as a blocking peptide with polyclonal antibody PA5-20945.
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Anaphase-promoting complex subunit 4; APC4; Cyclosome subunit 4
Gene Aliases: ANAPC4; APC4
UniProt ID: (Human) Q9UJX5
Entrez Gene ID: (Human) 29945
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