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This product contains purified recombinant human CAIII protein with an N-terminal hexahistidine tag.
This product may be used as a positive control in many immunological assays.
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10. 3 kb and contains seven exons and six introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CA III; CA-III; CAH3; CAIII (Muscle); Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III; carbonic anhydrase III, muscle specific; EC 4.2.1.1; epididymis secretory sperm binding protein Li 167mP; HEL-S-167mP
Gene Aliases: CA3; CAIII; Car3
UniProt ID: (Human) P07451
Entrez Gene ID: (Human) 761
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