Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Human Fc gamma RIIA (CD32a) (167 Arg) His-tag Recombinant Protein
Product Details
RP-87985
Product Specifications
Species
Human
Expression System
HEK293 cells
Amino acid sequence
Human FCGR2A, amino acids Met1-Ile218 (Accession # P12318-1, with Natural variant His 167 Arg) with a C-terminal His-tag
Tag
His-tag
Molecular weight
21.97 kDa
Class
Recombinant
Type
Protein
Purity
≥95% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.
Endotoxin concentration
<1.0 EU/µg
Activity
1. Measured by its ability to bind biotinylated human IgG2 in functional ELISA. 2. Loaded Anti-CD32A Antibody, Mouse Monoclonal on AMC Biosensor, can bind CD32A Protein, Human, Recombinant (167 Arg, His Tag) (RP-87985) with an affinity constant of 6.8 nM as determined by Octet RED System.
Conjugate
Unconjugated
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 5% mannitol, 5% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
Reconstituted with sterile deionized water to 1 mg/mL.
Concentration is measured by UV.
Target Information
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: CD32; CDw32; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc gamma receptor IIa; Fc-gamma RII-a; Fc-gamma-RIIa; fcRII-a; IgG Fc receptor II-a; Immunoglobulin G Fc receptor II; Low affinity immunoglobulin gamma Fc region receptor II-a
Gene Aliases: CD32; CD32A; CDw32; FCG2; FcGR; FCGR2; FCGR2A; FCGR2A1; IGFR2
UniProt ID: (Human) P12318
Entrez Gene ID: (Human) 2212
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support