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Product Details
RP-101704
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
TAMSVIGDRRSREQKAKQEREKELAKVTIKKEDLELIMTEMEISRAAAERSLREHMGNVVEALIALT
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63098. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Huntingtin-interacting protein K (HYPK) has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. It protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. HYPK is required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ20431; Huntingtin yeast partner K; Huntingtin-interacting protein K
Gene Aliases: C15orf63; HSPC136; HYPK
UniProt ID: (Human) Q9NX55
Entrez Gene ID: (Human) 25764
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