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Product Details
PEP-0507
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human IFN-b.
PEP-0507 can be used as a blocking peptide with polyclonal antibody PA5-20390.
Target Information
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fibroblast interferon; IFN b; IFN β; IFN-beta; IFNbeta; IFNβ; Interferon; Interferon b; Interferon beta; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1
Gene Aliases: IFB; IFF; IFN-beta; IFNB; IFNB1
UniProt ID: (Human) P01574
Entrez Gene ID: (Human) 3456
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