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Product Details
RP-75639
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
Amino acids Met1- Lys452 containing an N-terminal His-tag
Tag
His-tag
Molecular weight
55.92 kDa
Class
Recombinant
Type
Protein
Purity
>95%, by SDS-PAGE under reducing conditions
Conjugate
Unconjugated
Form
Liquid
Concentration
0.113 mg/mL
Purification
purified
Storage buffer
25mM sodium acetate, pH 4.8, with 50% glycerol
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
This product contains a purified 452 amino acid fragment (aa1-452) of mature human ILK1.
This product may be used as a positive control in many immunological assays.
Target Information
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 59 kDa serine/threonine-protein kinase; epididymis secretory protein Li 28; ILK-1; ILK-2; Inactive integrin-linked kinase; Integrin linked ILK; integrin-linked kinase; integrin-linked kinase-2; p59ILK; Scaffold protein ILK
Gene Aliases: HEL-S-28; ILK; ILK-1; ILK-2; ILK1; ILK2; P59; p59ILK
UniProt ID: (Human) Q13418
Entrez Gene ID: (Human) 3611
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