Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 15 amino acids near the amino terminus of KHDC1.
PEP-1616 can be used as a blocking peptide with polyclonal antibody PA5-34573. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability. KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs. KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities.
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Protein Aliases: KH homology domain-containing protein 1; MGC10818
Gene Aliases: bA257K9.4; C6orf147; C6orf148; Em:AC019205.8; KHDC1; NDG1
UniProt ID: (Human) Q4VXA5
Entrez Gene ID: (Human) 80759
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