Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 18 amino acid peptide near the carboxy terminus of human KREMEN1.
PEP-1563 can be used as a blocking peptide with polyclonal antibody PA5-34520. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. This protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dickkopf receptor; Kremen protein 1; Kringle domain-containing transmembrane protein 1; kringle-coding gene marking the eye and the nose; Kringle-containing protein marking the eye and the nose
Gene Aliases: KREMEN; KREMEN1; KRM1
UniProt ID: (Human) Q96MU8
Entrez Gene ID: (Human) 83999
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