Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (38%), Rat (38%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59105. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
SYCE1 (synaptonemal complex central element protein 1), also known as CT76 (cancer/testis antigen 76), is a 351 amino acid nuclear protein that belongs to the SYCE family and exists as three alternatively spliced isoforms. Colocalizing with SYCE2 on chromatin, SYCE1 exists as a homodimer and is found in the transverse central elements of the central region between lateral elements of the synaptonemal complexes (SCS). The transverse central element of the SCS is formed between homologous chromosomes during meiotic prophase and requires SYCP1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 76; CT76; Synaptonemal complex central element protein 1
Gene Aliases: C10orf94; CT76; POF12; SPGF15; SYCE1
UniProt ID: (Human) Q8N0S2
Entrez Gene ID: (Human) 93426
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