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Product Details
RP-43141
Product Specifications
Species
Human
Molecular weight
58.7 kDa
Class
Native
Type
Protein
Conjugate
Unconjugated
Form
Liquid
Concentration
7.6 mg/mL
Purification
SDS-PAGE
Storage buffer
0.05M potassium phosphate, pH 7.4, with 7.5mM KCl, 0.075mM EDTA
Contains
no preservative
Storage conditions
-80°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
RP-43141 contains native human a2-Plasmin Inhibitor protein.
RP-43141 may be used as a positive control in many immunological assays.
The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.
This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!
Target Information
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2; Serpin F2; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Gene Aliases: A2AP; AAP; ALPHA-2-PI; API; PLI; SERPINF2
UniProt ID: (Human) P08697
Entrez Gene ID: (Human) 5345
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