Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 18 amino acid peptide near the carboxy terminus of human VPS39.
PEP-1218 can be used as a blocking peptide with polyclonal antibody PA5-21104.
VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6. 5.
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Protein Aliases: hVam6p; OTTMUSP00000023341; OTTMUSP00000023350; PI3K type 3; TRAP1-like protein; vacuolar protein sorting 39 homolog; Vam6/Vps39-like protein; VPS39 HOPS complex subunit
Gene Aliases: hVam6p; KIAA0770; TLP; VAM6; VPS39
UniProt ID: (Human) Q96JC1
Entrez Gene ID: (Human) 23339
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