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Invitrogen
Mouse IL-16 Recombinant Protein
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Product Details
RP-8610
Product Specifications
Species
Mouse
Expression System
E. coli
Amino acid sequence
MHDLNSSTDS AASASAASDI SVESKEATVC TVTLEKTSAG LGFSLEGGKG SLHGDKPLTI NRIFKGDRTG EMVQPGDEIL QLAGTAVQGL TRFEAWNVIK ALPDGPVTIV IRRTSLQCKQ TTASADS
Molecular weight
13.2 kDa
Class
Recombinant
Type
Protein
Purity
≥95% by SDS-PAGE
Endotoxin concentration
≤0.1 EU/µg
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.1 mg/mL
Purification
purified
Storage buffer
10mM sodium phosphate, pH 7.5
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Recombinant mouse IL-16 is a non-glycosylated protein containing 127 amino acids.
Recombinant mouse IL-16 has full biological activity compared to a standard.
Reconstitute using sterile water at 0.1 mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20ºC and add 0.1% BSA for additional stability.
Target Information
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; ILN; Interleukin; Interleukin16; M-IL-16; Pro-interleukin-16
Gene Aliases: Il16; mKIAA4048
UniProt ID: (Mouse) O54824
Entrez Gene ID: (Mouse) 16170
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