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LC-MS Accessories
Optimize MS workflows and performance
Thermo Fisher Scientific offers a line of specialized ion sources, differential ion mobility, and probes that optimize MS workflows and performance to help you obtain the most sensitive data possible.
Browse our complete portfolio below, or let one of our experts help you tailor a selection specific to your application and workflow needs.
Popular products
VeriSpray PaperSpray ion source
Direct ionization technique minimizes sample prep, avoids chromatographic separation to obtain mass spectrometry sample analysis in 1-2 minutes.
FAIMS Pro Duo Interface
Field asymmetric ion mobility spectrometry provides unsurpassed LC-MS instrument selectivity and detection limits for proteomics applications.
OptiSpray Ion Source
Simplify the acquisition of high-quality, reproducible nano and capillary LC-MS data with automated spray optimization and cartridge columns.
Take your research to the next level with our broad portfolio of low-flow HPLC and UHPLC columns offering excellent sensitivity, resolution, and reproducibility.
Ionization sources for LC-MS
Thermo Fisher Scientific offers a wide range of ion sources suited to various analysis modes, including both nominal mass and high-resolution accurate-mass (HRAM) mass spectrometry, differential ion mobility, and paper chromatography.
Product | Description |
|---|---|
| OptiSpray Ion Source | An intelligent electrospray ionization interface that dramatically simplifies the acquisition of high-quality, reproducible nano and capillary LC-MS data for your most challenging biological samples, the OptiSpray ion source combines automated spray optimization with cartridge-based nano and capillary columns to deliver high-sensitivity, quantitative accuracy and precision, and maximum robustness for both discovery and targeted assays. |
| Electron Transfer Dissociation (ETD) | For improved sequence coverage and post-translational modification analysis of peptides and proteins, choose the ETD option for peptide fragmentation. This option can be used instead of, or in conjunction with, collision-induced dissociation (CID) on specific Orbitrap mass spectrometers. |
| FAIMS Pro Duo Interface | For challenging bioanalytical applications, including the accurate determination of pharmacokinetic parameters, high-Field Asymmetric waveform Ion Mobility Spectrometry (FAIMS) can be used to optimize ion selectivity and reduce chemical backgrounds during mass spectrometry assays. FAIMS successfully prevents interferences from co-eluting compounds and increases signal to noise ratios by 100-fold or higher. |
| VeriSpray PaperSpray Ion Source | Improve turnaround time, reduce cost per test and minimize sample preparation with a fully automated, fully integrated, high-throughput, direct ionization technique used with our newest triple quadrupole mass spectrometers. |
| Heated Electrospray Ionization (HESI-II) Probe | Enhance your LC-MS assays up to eight times by adding a HESI-II probe to your Thermo Scientific Ion Max ion source. The HESI-II probe provides better desolvation and improved nozzle performance, and is already a standard feature of many Thermo Scientific mass spectrometers. |
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