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Tandem Mass Tag Reagents
Shop from our array of tandem mass tag reagents designed for protein labeling and multiplexed quantitative analysis by mass spectrometry. These kits and reagents enable efficient protein identification and quantitation in various sample types. Tandem mass tag (TMT) reagents include isobaric and isotopic tagging compounds with amine-reactive NHS-ester groups, spacer arms, and mass reporters. Available in different multiplex options, such as TMTpro, TMT10plex, TMTsixplex, and TMTduplex, these reagents allow simultaneous analysis of up to 18 samples. Specialized variants like aminoxyTMT and iodoTMT target specific biomolecules. TMT reagents are suitable for labeling peptides, cell lysates, and proteins extracted from tissues or biological fluids, facilitating comparative proteomics studies and targeted quantitation experiments. Learn more about TMT systems and publications.
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TMT10plex Isobaric Label Reagents and Kits contain ten isobaric compounds with the same mass and chemical structure (i.e., isotopomeric) composed of an amine-reactive NHS-ester group, a spacer arm, and a mass reporter.
Thermo Scientific TMTpro label reagents are the next generation of tandem mass tags, designed to increase the level of sample multiplexing without compromising on protein identification and quantitation.
TMTpro label reagents are the next generation of tandem mass tags, designed to increase multiplexing without compromising protein identification and quantitation. The structures of the TMTpro and TMT tags are similar in being isobaric and amine reactive, but the TMTpro tag has a longer spacer region...
TMTpro label reagents are the next generation of tandem mass tags, designed to increase the level of sample multiplexing without compromising on protein identification and quantitation. The Thermo Scientific TMTpro 18plex Label Reagent Set enables multiplexing up to 18 samples, enabling even greater...
The Thermo Scientific TMTzero Label Reagent serves as a 'light' tag for MS-level peptide quantitation similar to duplex isotopic metabolic labeling, such as SILAC, or isotopic dimethylation labeling.
Amine-reactive Thermo Scientific TMT Isobaric Mass Tagging Kits and Reagents enable multiplex quantitation of proteins extracted from cells and tissues from up to 6 samples using tandem mass spectrometry.
Tandem mass tag (TMT) reagents are specially designed to enable identification and quantitation of proteins in different samples using tandem mass spectrometry. The TMT11-131C tag structure is identical to the other TMT10pex tags, but the TMT11-131C mass reporter is labeled with only 13C isotopes.
The Thermo Scientific TMTpro 10plex Label Reagent Set (Unit Mass Reporter), 1 x 5 mg enables multiplexing of up to 10 samples for simultaneous analysis on lower resolution MS instruments.
Thermo Scientific TMTpro Zero Label Reagent serves as a 'light' tag for MS-level peptide quantitation for method optimization or use with the TMTpro 16 plex Label Reagent Set.
Amine-reactive Thermo Scientific TMT Isobaric Mass Tagging Kits and Reagents enable multiplex quantitation of proteins extracted from cells and tissues from up to 6 samples using tandem mass spectrometry.
Pre-formulated TEAB and 50% hydroxylamine designed for use in TMT labeling and quenching of peptides.
TMTduplex™ Isobaric and Isotopic Mass Tagging Reagent sets enable 2-way labeling experiments of extracted proteins using tandem mass spectrometry.
Thermo Scientific iodoTMT Label reagents enable multiplexed identification and quantitation of cysteine containing peptides in different samples using tandem mass spectrometry. IodoTMT reagents are sets of isobaric (mass and structure) isomers that are iodoacetyl-activated for covalent, irreversible...
TMTduplex™ Isobaric and Isotopic Mass Tagging Reagent sets enable 2-way labeling experiments of extracted proteins using tandem mass spectrometry.
Thermo Scientific Pierce TMT11plex Yeast Digest Standard is a lyophilized yeast peptide mixture of four congenic yeast strains labeled with TMT11plex reagents to monitor LC-MS/MS system performance for multiplexed quantitation.
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Tandem mass tags (TMT) are robust and efficient systems for multiplex, relative protein quantitation of up to 35 samples, derived from cells, tissues, or biological fluids. All mass tagging reagents within a label reagent set have the same nominal mass (i.e.
For nine years, Thermo Scientific awarded grants to doctoral and post-doctoral students that proposed studies utilizing tandem mass tag labeling reagents in their research. Learn about past award recipients in the tabs below.
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What is the main purpose of TMT (Tandem Mass Tag) reagents?
What is the main purpose of Tandem Mass Tag (TMT) reagents?