Protein Digestion Chromatography Sample Preparation Kits

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None (11)
None (1)

C-terminal side of lysine and arginine amino acids (12)
Degrades single-stranded RNA at C & U residues (1)
Degrades single-stranded RNA at G residues (1)
Pepsin: Cleaves proteins preferentially at carboxylic groups of aromatic amino acids such as phenylalanine, tryptophan and tyrosine. The optimum pH range for pepsin activity is 1.0–3.0.

Protease XIII: Cleaves proteins preferentially at carboxylic groups of basic amino acids (arginine, lysine, histidine). Like pepsin, Proteinase XIII is active at low pH. (1)

Pepsin & Protease XIII (1)
RNase A (1)
RNase T1 (1)
Trypsin (12)

SMART Digest Low pH Resin Pre-filled into PCR Tubes (1)
SMART Digest Resin Pre-filled into PCR Tubes (3)
SMART Digest Resin, Bulk Magnetic (3)
SMART Digest Resin, Bulk Non-magnetic (3)
SMART Digest Soluble Trypsin (2)

SMART Digest (12)

Protein Digestion (11)
Protein Digestion, MAM (1)
SMART Digest Pepsin/Protease XIII Dual Enzyme column (1)
SMART Digest RNase A column (1)
SMART Digest RNase T1 column (1)

SMART Digest™ Trypsin Kits

Obtain high quality analytical results from protein digests using Thermo Scientific™ SMART Digest™ Kits. A significant advance in sample preparation for biopharmaceutical protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels...

SMART Digest™ Dual Enzyme Columns for HDX-MS Analysis

Thermo Scientific SMART Digest Dual Enzyme columns containing pepsin and protease XIII provide fast, reliable digestion of proteins for for HDX-MS analysis helping to provide the sequence characterization of biotherapeutics.

SMART Digest RNase Columns

Thermo Scientific SMART Digest Immobilized Ribonucleases (Rnases) Columns are designed using the same proven technology as the Thermo Scientific SMART Digest Rnase kits to provide simple, fast and highly reproducible digestion of ribonucleic acid (RNA) in a flow through format.

Chromatography Sample Preparation

Sample preparation is a key step in analytical workflow. Our solutions include a multitude of consumables and automated platforms to enable fast, reproducible and easy sample preparation whatever your workflow requirements may be.

LC-MS Protein Sample Preparation Kits

Liquid chromatography-mass spectrometry (LC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) are key techniques in proteomic research studies. High-quality preparation of protein to peptide samples for LC-MS and LC-MS/MS is essential for high-quality results.

Product FAQ

Why is the processing time for MS analysis less with SureQuant IP-MS Sample Preparation kits compared to traditional IP methods?

Product FAQ

Can I use SureQuant Protein A/G and SureQuant Streptavidin IP-MS Sample Preparation kits with any sample?