siRNA

Silencer® Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry. Silencer® Select Pre-Designed siRNAs are guaranteed-to-silence based on their proven design.

Silencer® Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry. Silencer® Select Validated siRNAs are functionally tested to reduce target gene expression.

RNA interference (RNAi) is the best way to effectively knock down gene expression to study protein function in a wide range of cell types. Use our GeneAssist™ Custom siRNA Builder to design and order a custom siRNA.

Using our award-winning BLOCK-iT™ RNAi Designer, you can design Custom BLOCK-iT™ siRNA sequences for efficient and specific gene expression knockdowns in any organism. For enhanced target specificity and stability in serum, Stealth RNAi™ RNAi chemistry is available.

Silencer® Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry. Silencer® Select Validated siRNAs are functionally tested to reduce target gene expression.

Ambion™ fluorescently labeled control siRNA for the easy monitoring of siRNA uptake by fluorescence microscopy along with siRNA-induced knockdown. Purified, annealed, and ready to use, the 5 nmol aliquot is supplied in a stable, dried format.

Silencer® Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry. Silencer® Select Pre-Designed siRNAs are guaranteed-to-silence based on their proven design.

Transcription factors are fast becoming promising drug targets, as they bind to and regulate the transcription of genes. The Silencer™ Select Human Transcription Factor siRNA Library targets genes expressing proteins that bind DNA in a sequence-specific manner to control the rate of transcription of...

RNA interference (RNAi) is the best way to effectively knock down gene expression to study protein function in a wide range of cell types. Use our GeneAssist™ Custom siRNA Builder to design and order a custom siRNA.

Ambion™ fluorescently labeled control siRNA for the easy monitoring of siRNA uptake by fluorescence microscopy along with siRNA-induced knockdown. Purified, annealed, and ready to use, the 5 nmol aliquot is supplied in a stable, dried format.

Cell surface receptors are specialized integral membrane proteins that take part in communication between the cell and its surroundings. Extracellular signaling molecules, typically hormones, neurotransmitters, cytokines, growth factors and cell recognition molecules, attach to the receptor,...

Transcription factors are fast becoming promising drug targets, as they bind to and regulate the transcription of genes. The Silencer Human Transcription Factor siRNA Library targets genes expressing proteins that bind DNA in a sequence-specific manner to control the rate of transcription of genetic...

For the first time, you can obtain the benefits of Ambion™Silencer™ Select siRNAs in a convenient pre-plated, library format. These siRNA collections enable medium and high throughput analysis of phenotypes resulting from inhibition of large sets of targets from specific functional classes.

The Silencer™ Human Drug Targets siRNA Library includes genes involved in apoptosis, senescence, nucleic acid binding, autophagy, DNA repair, and along with characterized nuclear receptors and other genes that are considered potential targets for therapeutics.

Transporter proteins play a key role in pharmacology, affecting how molecules are moved across cellular membranes. The Silencer™ Human Drug Transporter siRNA Library includes genes important to the absorption, distribution, metabolism and excretion of many drugs.