Trifluoroacetic Acid

Trifluoracetic acid is an organofluorine compound that is a structural analogue of acetic acid with all three of the acetyl group’s hydrogen atoms replaced by fluorine atoms. It is stronger than acetic acid, having an acid ionization constant of pKA 0.23. Trifluoracetic acid is available in various quantities and reagent grades. It is widely used in organic synthesis, mass spectrometry, and NMR spectroscopy.
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Thermo Scientific™ Pierce Trifluoroacetic Acid (TFA) is manufactured and tested to meet strict specifications that ensure superior performance for use as an ion-pairing agent in reverse-phase peptide separations.
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to...
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to...
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to...
The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis.
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals,...
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to...
The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis.
Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis.
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals,...
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The most commonly used solvents or solvent blends include LC-MS grade water and acetonitrile, with ion pairing agents such as trifluoroacetic acid (TFA), formic acid (FA) or heptafluorobuteric acid (HFBA). These solvents are available as single component formulations or convenient blends.
Linker phosphoramidites provide options to link oligonucleotides to additional groups (e.g., chemical delivery system for therapeutics, fluorescent dyes, amines, phosphates) or attach to a solid surface like a DNA chip.
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What kind of buffers and solutions are compatible with peptide clean-up and LC-MS?
What is the composition of the Binding/Wash Buffer in the High-Select Fe-NTA Phosphopeptide Enrichment Kit and High-Select Fe-NTA Magnetic Phosphopeptide Enrichment Kit?