HPLC Ion Pair Reagents

Solutions of various chemical compositions formulated for use as ion-pairing agents in HPLC and mass spectrometry applications.
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Formic Acid, LC-MS Grade Thermo Scientific™
Thermo Scientific™ Formic Acid is high-purity solvent supplied in glass ampules as a convenient, contamination-free alternative for preparing elution solvents for HPLC separations of protein and peptides.
Thermo Scientific™ Pierce Trifluoroacetic Acid (TFA) is manufactured and tested to meet strict specifications that ensure superior performance for use as an ion-pairing agent in reverse-phase peptide separations.
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By using the correct reagent, you can increase or decrease retention and control selectivity, resolve complex ionic mixtures without using ion exchange columns, and improve peak symmetry. Also see our ultrapure solvents for high-sensitivity HPLC and LC-MS analysis, and special reagents for amino...
Perform heating, stirring, and evaporation in a single system for a complete solution to conducting derivatization and other small-scale reactions with reliability and ease. The Thermo Scientific Reacti-Therm Sample Derivatization System can assist with gas chromatography (GC) sample preparation,...
Documents & Support (131)
Application brief: Improvements in reversed phase chromatography of bisphosphonates with the use of ion pairing reagents
Product Spotlight: Oligonucleotide characterization using μPAC columns in ion-pairing reversed-phase high performance liquid chromatography mode