HCS and HCA Resources

Learn more about our platforms

Find out what other scientists who use Thermo Scientific CellInsight High-Content Screening platforms are saying about the performance of these instruments in their research. Check out our instrument demos and videos, the education and training webinars, tools and protocols, documents, and patents. We highly encourage you to register your HCS platform. Browse through our comprehensive Cell Imaging Support Center for all additional support. 

Scientist stories

2:29

3D culture screening

Michael Johnson and his team at Visikol
1:49

RNA in cancer cells

Dr. Kaylene Simpson, Peter MacCallum Cancer Center
5:31

Dependable cell-based assays

James Evans, CEO of PhenoVista Biosciences
4:07

Imaging assays with co-cultured cells

Anthony Essex, CTO of PhenoVista Biosciences

Here is what users of Thermo Scientific high-content screening are saying.

"What the CX7 LZR really allowed us to do is to screen a number of samples in a much shorter amount of time without having so much user input."

Dr. Erin Edwards,

In Vitro Services Director, Visikol

"The CX7 HCS platform has been a tremendous addition to our fleet, it has far more superior capabilities than the older versions we have, but the most important part is that we now have confocality. Bringing in the CX7 has really been able to open up what we can offer to the broader screening community."

Dr. Kaylene Simpson,

Peter MacCallum Cancer Center

"Our business at PhenoVista is providing data to our clients and we have deadlines every single day, so we need a reliable platform, and the Thermo Fisher Scientific CX7 works really reliably."

James Evans,

CEO of PhenoVista Biosciences

"The CX7 HCS platform allows us to multiplex up to 5 fluorescent colors in a single sample, it's incredibly fast, incredibly reliable, and easy to use. One exciting feature of this microscope is its confocal capability which allows us to pick which focal plane we want to look at any given time!"

Anthony Essex,

CTO of PhenoVista Biosciences

Demos and videos

CellInsight CX7 LZR

1:00

Introducing the Thermo Scientific CX7 LZR High-Content Screening Platform

The CellInsight CX7 LZR is a fast, laser-based, automated cellular imaging and analysis platform for quantitative microscopy and phenotypic screening. It’s designed to provide you with the sensitivity and speed that’s needed for emerging assays.
4:22

Introducing the Thermo Scientific CX7 LZR High-Content Screening Platform

The Thermo Scientific CellInsight CX7 LZR High Content Analysis Platform is a fast, laser-based, automated cellular imaging and analysis platform for quantitative microscopy and phenotypic screening.

Q&A video series

1:28

How can I analyze thick samples using confocal imaging and high-content screening?

Video describes why confocal imaging and analysis is particularly well suited for analyzing thicker sample types.
1:28

How difficult is it to operate a high-content analysis instrument?

How difficult is it to operate a high-content analysis instrument and is a dedicated resource needed?
1:54

HCA Q&A - What is high-content?

What is high-content and is there a difference between the terms high-content screening and high-content analysis?
1:36

How difficult is it to operate high-content screening software?

Video discusses recent innovations in HCA analysis software that make it easy to learn and operate by making the user interface streamlined with descriptive menus and providing workflow monitoring for efficient real-time tracking.
2:00

Imaging plate reader vs. high-content analysis platform

What is the difference between an imaging plate reader and a high-content analysis platform?
2:33

Live-cell action and response using high-content imaging?

Video discusses considerations for imaging live cells, including strategies to minimize phototoxicity, increase cell tracking, provide an optimal environment for the cells, and obtain accurate measurements.

Education and training

Webinars

1:01:14

Practical considerations for designing and executing high-content screens

Watch this webinar to learn HCS basics, assay design tips, and explore Cell Painting with real use cases across various disease areas.
1:04:43

Practical considerations for fluorescent cell staining and microscopy in cancer cell biology research

This webinar discusses practical considerations for fluorescent cell staining and microscopy in cancer cell biology research.
22:33

Democratizing High-Content Screening Multiparameter Applications With the New CellInsight CX7 Pro Series

This video focuses on the multi-parameter applications of the CX7 Pro series including FirePlex and Cell Painting.
6:41

High-Content Screening of 3D Organoids with Amira Software

This video demonstrates how Amira software is applied in a CX7 high-content screening platform to study 3D organoids.
1:13:01

Driving drug-efficient, effective drug discovery using machine learning models of tumor drug response

Helomics has developed a novel platform that allows the screening of compounds against thousands of tumors using a combination of a clinically validated patient derived tumors, highly annotated high-content based tumor drug response profiles
49:03

Investigating three-dimensional life sciences biologies using high-content technology

This technical seminar will provide an overview of pharmacological applications where the technology is applied for drug discovery in the 3-D space.
51:57

Delivering bespoke high-content assay services to the drug discovery community

High content analysis presents many challenges to its practitioners including but not limited to meticulous sample preparation, an understanding of the biology and the questions posed, comfort with image analysis and interpretation
1:02:07

2020 SBI2 Thermo Fisher Scientific roundtable discussion on virology and high-content screening

Roundtable discussion on virology and high-content screening
38:44

Multiplex imaging and analysis of slides using high-content imaging

In this presentation we will discuss a rapid and easy-to-use approach for the multiplexed labeling and imaging of tissues using a CX7 LZR high content confocal system which allows for the detailed interrogation of the tumor microenvironment

High-content screening patents

Patents on high-content screening-analysis (HCS/HCA) products

Product name

Patent Number
  • ArrayScan XTI HCA Reader
  • ArrayScan Infinity HCS Reader

AU 730100; CA 2,282,658; CA 2,328,194; CA 2,362,117; CA 2,381,334; EP 0983498; EP 1095277; EP 1155304; EP 1203214; EP 1314980; EP 1368689; JP 3466568; JP 3576491; JP 3683591; JP 3683591; JP 4011936; US 5,989,835; US 6,416,959; US 6,573,039; US 6,620,591; US 6,671,624; US 6,716,588; US 6,727,071; US 6,759,206; US 6,875,578; US 6,902,883;  US 6,970,789; US 6,986,993; US 7,060,445; US 7,085,765;  US 7,117,098; US 7,160,687; US 7,235,373; US 7,476,510; US 7,853,409; US 8,050,868; US 8,062,856; US 8,103,457
  • Cellinsight NXT HCS Platform

AU 730100; CA 2,282,658; CA 2,328,194; CA 2,362,117;  CA 2,381,334; EP 0983498; EP 1095277; EP 1155304; EP 1203214;  EP 1314980; EP 1368689; JP 3466568; JP 3576491; JP 3683591;  JP 4011936; US 5,989,835; US 6,416,959; US 6,573,039; US 6,620,591; US 6,671,624; US 6,716,588; US 6,727,071;  US 6,759,206; US 6,875,578; US 6,902,883; US 6,970,789;  US 6,986,993; US 7,060,445; US 7,085,765; US 7,117,098; US 7,160,687; US 7,235,373; US 7,476,510; US 7,853,409;  US 7,853,411; US 8,050,868; US 8,062,856; US 8,103,457
  • ToxInsight IVT Platform

AU 730100; CA 2,282,658; CA 2,362,117; CA 2,381,334; EP 0983498; EP 1155304; EP 1203214; EP 1314980; EP 1368689; JP 3576491; JP 3683591; JP 4011936; US 5,989,835; US 6,416,959; US 6,573,039; US 6,620,591; US 6,671,624; US 6,727,071; US 6,875,578; US 6,902,883; US 6,970,789; US 6,986,993; US 7,060,445; US 7,085,765; US 7,117,098; US 7,160,687; US 7,235,373; US 7,476,510; US 7,853,409; US 8,050,868; US 8,062,856; US 8,103,457
  • ToxInsight CHPS Platform

AU 730100; CA 2,282,658; CA 2,328,194; CA 2,362,117; CA 2,381,334; EP 0983498; EP 1095277; EP 1155304; EP 1203214; EP 1368689; JP 3466568; JP 3576491; JP 3683591; JP 4011936; US 5,989,835; US 6,416,959; US 6,573,039; US 6,620,591; US 6,671,624; US 6,759,206; US 6,875,578; US 6,902,883; US 6,970,789; US 6,986,993; US 7,060,445; US 7,085,765; US 7,117,098; US 7,235,373; US 7,853,409; US 7,853,411; US 8,050,868; US 8,062,856; US 8,103,457
  • ArrayScan Live Cell Module

AU 730100; EP 1348124; US 6,917,884; EP 1203214; EP 1314980
  • Cellomics ONE Platinum BioApplication Suite
  • Insight ONEBioApplication Suite

AU 730100; CA 2,282,658; CA 2,328,194; CA 2,362,117; CA 2,381,334; EP 0983498; EP 1095277; EP 1155304; EP 1203214; EP 1314980; JP 3466568; JP 3576491; JP 3683591; JP 4011936; US 5,989,835; US 6,416,959; US 6,573,039; US 6,620,591; US 6,671,624; US 6,716,588; US 6,727,071; US 6,759,206; US 6,875,578; US 6,902,883; US 6,986,993; US 7,060,445; US 7,117,098; US 7,160,687; US 7,235,373; US 7,476,510; US 7,853,409; US 7,853,411; US 8,050,868; US 8,062,856; US 8,103,457
  • vHCS Discovery Toolbox  
  • iDev Assay Development Workflow
  • HCS Studio

AU 730100; CA 2,282,658; CA 2,328,194; CA 2,362,117; CA 2,381,334; EP 0983498; EP 1095277; EP 1155304; EP 1203214; EP 1314980; EP 1368689; JP 3466568; JP 3576491; JP 3683591; JP 3683591; JP 4011936; US 5,989,835; US 6,416,959; US 6,573,039; US 6,620,591; US 6,671,624; US 6,716,588; US 6,727,071; US 6,759,206; US 6,875,578; US 6,902,883; US 6,970,789; US 6,986,993; US 7,060,445; US 7,085,765; US 7,117,098; US 7,160,687; US 7,235,373; US 7,476,510; US 7,853,409; US 8,050,868; US 8,062,856; US 8,103,457
  • vHCS View
  • HCSExplorer

AU 730100; CA 2,282,658; EP 0983498; JP 3683591
  • Cellomics Store

AU 773088; CA 2,350,587; CA 2,410,688; EP 1145149; EP 1439384; US 7,467,153; US 8,024,293; US 8,090,748

Registering your HCS platform

To receive notifications of software and firmware updates, special offers on HCS reagents, and tips and tricks to optimize the use of your HCS instrument, register your HCS instrument here!

Cell imaging support center

In Cell Imaging Support, part of our Cell Analysis Support Center, you can find tips and troubleshooting suggestions for high-content screening instruments as well as other Thermo Fisher Scientific cell imaging systems. These resources include getting started and troubleshooting FAQs, guide and tools, online resources, training, events, and webinars, and much more.

Thermo Scientific 2021 High-Content Screening Technology Expert Seminar Series

High Content Screening Expert Seminar Series! Hear from expert scientists using the Thermo Scientific CellInsight and ArrayScan instruments and learn from their experiences.  Topics included over the 4-part series include developing oncological assays using 3D models, pharmacological analysis for Alzheimer’s and Parkinson’s Diseases, multifunctional approaches to pharmacological screening, and use to examine HIV infection and inflammation in macrophages.

 

Join us for our 2021 North American High Content Screening Expert Seminar Series!

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    Harness the power of 3D models in the research of cancer

    Nicholas Radio, Global Product Manager, High-Content Screening

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      3D high content processing and visualization for the CellInsight platform

      Dr. Rengarajan Pelapur, Global Manager, Product Applications Specialists, Thermo Fisher Scientific

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        Using high-content imaging to examine HIV infection and inflammation in macrophages

        Dr. Peter Gaskil, Associate Professor, Department of Pharmacology and Physiology at Drexel University College of Medicine

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          Multifunctional approach to pharmacologic screening (MAPS) reveals novel vulnerabilities in cells

          Isaac Harris, Assistant Professor, University of Rochester Medical School, Wilmot Cancer Institute

          For Research Use Only. Not for use in diagnostic procedures.

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