Decorative image of POROS family of chromatography columns

POROS analytical chromatography columns are used for the quantification and assessment of purity of biomolecules throughout cell culture and purification processes. POROS A, G, AL, EP, OH, and POROS CaptureSelect columns are polymeric packings designed for high-resolution separation, specifically affinity chromatography of antibodies, proteins, polynucleotides, and other biomolecules with user-immobilized ligands. The resins consist of cross-linked poly[styrene-divinylbenzene] (DVB) flow-through particles for rapid mass transport. This base bead is coated with a cross-linked polyhydroxylated polymer (POROS OH), which is then activated with aldehyde (POROS AL) or epoxide (POROS EP) functional groups.


Figure 1. POROS A, G, and CaptureSelect ligands target multiple IgG epitopes. Figure 1 illustrates the binding sites for affinity ligands Protein A, Protein G, and Protein L. Novel POROS ligands provide alternative specificities that enable rapid binding for the quantitation or purification of engineered immunoglobulins.

Note: POROS affinity chromatography columns are shown in orange.

Ordering information

POROS A, G, and ligands are available in convenient prepacked HPLC columns. The column range addresses analytical and preparative requirements for the quantitation and purification of immunoglobulins or Fc-fusion or HSA-fusion proteins.

Affinity resin columns
POROS A 20 µm Columns

POROS™ Prepacked Protein A Affinity Column is based on an immobilized recombinant Protein A functional group designed for high-throughput purification of antibodies.

Catalog # Name Size Price (USD) Qty
2100100 POROS™ A 20 μm Column, 2.1 x 30 mm, 0.1 mL Each
1,644.00
1502226 POROS™ A 20 μm Column, 4.6 x 100 mm, 1.7 mL Each
2,085.00
1502224 POROS™ A 20 μm Column, 4.6 x 50 mm, 0.8 mL Each
1,754.00
1502412 POROS™ A 20 μm Column, Stainless Steel, 2.1 x 30 mm, 0.1 mL Each
1,642.00
POROS A 50 micron Columns:
POROS G 20 µm Columns

POROS™ Prepacked Protein G Affinity Column is based on an immobilized recombinant Protein G functional group designed for high-throughput purification of antibodies.

Catalog # Name Size Price (USD) Qty
2100200 POROS™ G 20 μm Column, 2.1 x 30 mm, 0.1 mL Each
1,654.00
1512226 POROS™ G 20 μm Column, 4.6 x 100 mm, 1.7 mL Each
2,755.00
1512224 POROS™ G 20 μm Column, 4.6 x 50 mm, 0.8 mL Each
2,085.00
POROS HE 50 – Columns
POROS MC µm Columns
Activated affinity
POROS AL 20 µm Columns

POROS™ Prepacked Immobilized Aldehyde Affinity Column is based on an aldehyde functional group designed for the immobilization of proteins through free amine groups.

Catalog # Name Size Price (USD) Qty
1602212 POROS™ AL 20 μm Column, 2.1 x 30 mm, 0.1 mL Each
1,272.00
1602226 POROS™ AL 20 μm Column, 4.6 x 100 mm, 1.7 mL Each
1,642.00
1602224 POROS™ AL 20 μm Column, 4.6 x 50 mm, 0.8 mL Each
1,370.00
4481822 POROS™ CaptureSelect™ FSH Affinity Column, 2.1 x 30 mm Each
3,145.00
4481826 POROS™ CaptureSelect™ FSH Affinity Column, 4.6 x 100 mm Each
3,980.00
4481824 POROS™ CaptureSelect™ FSH Affinity Column, 4.6 x 50 mm Each
3,240.00
POROS EP 20 µm Columns

POROS™ Prepacked Immobilized Epoxide Affinity Column is based on an epoxide functional group designed for the immobilization of proteins through free amine groups.

Catalog # Name Size Price (USD) Qty
1612226 POROS™ EP 20 μm Column, 4.6 x 100 mm, 1.7 mL Each
1,506.00
1612224 POROS™ EP 20 μm Column, 4.6 x 50 mm, 0.8 mL Each
1,352.00
POROS OH 50 Micron columns
POROS AL 20 Activated Affinity Resins (Aldehyde)
Catalog # Name Size Price (USD) Qty
1602906 POROS™ 20 AL Aldehyde Activated Resin Each
4,045.00
POROS HP2
POROS™ OH 20 - Lab Scale Columns (Hydroxylated)
POROS CaptureSelect
POROS CaptureSelect HSA – Lab Scale Columns
POROS CaptureSelect IgG Fc – Lab Scale Columns
POROS CaptureSelect IgM – Lab Scale Columns
POROS CaptureSelect LC Lambda – Lab Scale Columns
POROS CaptureSelect FSH – Lab Scale Columns
POROS CaptureSelect GCSF – Lab Scale Columns
HCG
FCXL
POROS CaptureSelect hGH – Lab Scale Columns
CH1-XL
POROS CaptureSelect IgA – Lab Scale Columns
POROS CaptureSelect KappaXL

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