Target Information
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin gamma 1 is a cytoplasmic actin found in nonmuscle cells.
Synonyms
ACT; ACTA1; ACTB; Actg; Actg1; actin; actin beta; actin gamma; actin gamma 1; actin homolog; actin, alpha 1, skeletal muscle; actin, beta; actin, cytoplasmic 1; Actin, cytoplasmic 1, N-terminally processed; Actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; Actin, cytoplasmic type 5; actin, cytoplasmic, type 5; Actin, gamma 1; actin, gamma 1 propeptide; actin, gamma, cytoplasmic 1; Actl; Actx; AL023024; Atcb; beta actin; beta cytoskeletal actin; beta-actin; beta-actin FE-3; BRWS1; BRWS2; cytoplasmic 2; cytoplasmic ACTG1; cytoplasmic actin; cytoplasmic type 5; cytoskeletal gamma-actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; DFNA20; DFNA26; E430023M04Rik; E51; epididymis luminal protein 176; gamma 1 propeptide; gamma-actin; HEL-176; PS1TP5-binding protein 1; PS1TP5BP1; type 5