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This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
0610010I13Rik; AI314617; BC019483; CSE; Cth; cth protein; CTL target antigen; Cys3; cystathionase; cystathionase (cystathionine gamma-lyase); cystathionase isoform 1; cystathionine gamma-lyase; Cystathionine gamma-lyase-like protein; cysteine desulfhydrase; cysteine-protein sulfhydrase; EGK_00877; fb58d08; gamma-cystathionase; H; homoserine deaminase; homoserine dehydratase; LOC102117863; MGC9471; PRB-RA; probasin-related antigen; QccE-22305; synthase; Unknown (protein for MGC:85785); wu:fb48e03; wu:fb58d08; zgc:66001; zgc:85785
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