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This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.
4930533O14Rik; C86324; Dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; Dipeptidyl peptidase 3; dipeptidyl peptidase III; dipeptidylpeptidase 3; dipeptidyl-peptidase 3; dipeptidylpeptidase III; dipeptidyl-peptidase III; DPP III; Dpp3; DPPIII; Enkephalinase B; hCG_2016942
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