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The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
cb291; Fiz; Fre; FREOS1; frezzled; Fritz; frizzled homolog-related; frizzled protein homolog; frizzled related protein; frizzled-related protein; frizzled-related protein 1; Frp; FRP-3; Frzb; Frzb precursor; FRZB1; FRZB-1; FRZB1sFRP-3; FRZB-PEN; fzb1; fzb-1; FZRB; hFIZ; id:ibd5075; ik:tdsubc_2e7; OS1; secreted frizzled-related protein 3; secreted frizzled-related sequence protein 3; SFRP3; sFRP-3; SFRP3frezzled; SRFP3; xx:tdsubc_2e7
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