HBS1L Antibodies

HBS1L antibodies from Thermo Fisher Scientific

Learn more about HBS1L primary antibodies that can be used in Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation in Human, Mouse, Rat and Non-human primate samples.

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Target Information

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Synonyms

2810035F15Rik; AI326327; EF-1a; eRF3 family member; eRF3c; ERF3-similar protein; ERFS; eukaryotic release factor 3; Hbs1; HBS1 like translational GTPase; HBS1L; Hbs1-like (S. cerevisiae); HBS1-like protein; HBS1-like translational GTPase; Hsp70 subfamily B suppressor 1-like protein; HSPC276; Kiaa1038