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This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.
1500032O14Rik; 2310034D06Rik; 4921513A11; C81073; CMD1GG; Flavoprotein subunit of complex II; FP; im:7141001; mitochondrial succinate dehydrogenase complex subunit A; PGL5; SDH1; SDH2; SDHA; SDHA protein; SDHF; SDHFP1; si:dkeyp-84f11.2; succinate dehydrogenase [ubiquinone] flavoprotein subunit; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; succinate dehydrogenase complex flavoprotein subunit A; succinate dehydrogenase complex subunit A; succinate dehydrogenase complex subunit A flavoprotein; succinate dehydrogenase complex subunit A, flavoprotein (Fp); succinate dehydrogenase complex, subunit A, flavoprotein (Fp); succinate dehydrogenase flavoprotein subunit; succinate dehydrogenase flavoprotein subunit A; zgc:56051
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