Product References
A single-cell transcriptional atlas reveals resident progenitor cell niche functions in TMJ disc development and injury.
Nature communications
Bi R,Yin Q,Li H,Yang X,Wang Y,Li Q,Fang H,Li P,Lyu P,Fan Y,Ying B,Zhu S
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2023
A single-cell transcriptional atlas reveals resident progenitor cell niche functions in TMJ disc development and injury.
Nature communications
Bi R,Yin Q,Li H,Yang X,Wang Y,Li Q,Fang H,Li P,Lyu P,Fan Y,Ying B,Zhu S
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2023
Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection.
Immunity
Xu W,Snell LM,Guo M,Boukhaled G,Macleod BL,Li M,Tullius MV,Guidos CJ,Tsao MS,Divangahi M,Horwitz MA,Liu J,Brooks DG
14-0902-82 was used in Miscellaneous to examine how chronic viral infections alter the pulmonary microenvironment to foster coinfection and worsen disease severity.
Tue Mar 09 00:00:00 EST 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis.
Nature communications
Beckmann D,Römer-Hillmann A,Krause A,Hansen U,Wehmeyer C,Intemann J,de Gorter DJJ,Dankbar B,Hillen J,Heitzmann M,Begemann I,Galic M,Weinhage T,Foell D,Ai R,Kremerskothen J,Kiener HP,Müller S,Kamradt T,Schröder C,Leitão E,Horsthemke B,Rosenstiel P,Nordström K,Gasparoni G,Gasparoni N,Walter J,Li N,Yang X,Chung HR,Pavenstädt H,Lindemann N,Schnittler HJ,Wang W,Firestein GS,Pap T,Korb-Pap A
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Immunohistochemistry
Tue Jun 15 00:00:00 EDT 2021
CD8 T Cells and STAT1 Signaling Are Essential Codeterminants in Protection from Polyomavirus Encephalopathy.
Journal of virology
Mockus TE,Netherby-Winslow CS,Atkins HM,Lauver MD,Jin G,Ren HM,Lukacher AE
14-0902-82 was used in Flow Cytometry to define biomarkers to stratify risk of progressive multifocal leukoencephalopathy and develop anti-JC polyomavirus interventions in patients suffering from progressive multifocal leukoencephalopathy.
Tue Mar 31 00:00:00 EDT 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis.
JCI insight
Redente EF,Chakraborty S,Sajuthi S,Black BP,Edelman BL,Seibold MA,Riches DW
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2020
Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.
JCI insight
Wu R,Ma F,Tosevska A,Farrell C,Pellegrini M,Deb A
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Thu Dec 17 00:00:00 EST 2020
Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation.
JCI insight
Kono M,Maeda K,Stocton-Gavanescu I,Pan W,Umeda M,Katsuyama E,Burbano C,Orite SYK,Vukelic M,Tsokos MG,Yoshida N,Tsokos GC
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that CaMK4 binds to PKM2 and promotes its activity, which is requisite for Th1 and Th17 differentiation.
Thu Jun 20 00:00:00 EDT 2019
IL-21 Controls ILC3 Cytokine Production and Promotes a Protective Phenotype in a Mouse Model of Colitis.
ImmunoHorizons
Poholek CH,Dulson SJ,Zajac AJ,Harrington LE
14-0902 was used in Flow cytometry/Cell sorting to reveal a novel role for IL-21 in shaping innate lymphoid cell responses in the intestine and provide one mechanism by which effector CD4 T cells can influence innate immunity.
Tue Jun 04 00:00:00 EDT 2019
Discovery of a periosteal stem cell mediating intramembranous bone formation.
Nature
Debnath S,Yallowitz AR,McCormick J,Lalani S,Zhang T,Xu R,Li N,Liu Y,Yang YS,Eiseman M,Shim JH,Hameed M,Healey JH,Bostrom MP,Landau DA,Greenblatt MB
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells.
The Journal of experimental medicine
Seki A,Rutz S
14-0902 was used in Flow cytometry/Cell sorting to develop an optimised approach for Cas9/RNP transfection of primary mouse and human T cells without TCR stimulation, that results in near complete loss of target gene expression at the population level.
Mon Mar 05 00:00:00 EST 2018
Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte.
Nature
Liu Z,Wang L,Welch JD,Ma H,Zhou Y,Vaseghi HR,Yu S,Wall JB,Alimohamadi S,Zheng M,Yin C,Shen W,Prins JF,Liu J,Qian L
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Immunofluorescence
Thu Nov 02 00:00:00 EDT 2017
Neuronal regulation of type 2 innate lymphoid cells via neuromedin U.
Nature
Cardoso V,Chesné J,Ribeiro H,García-Cassani B,Carvalho T,Bouchery T,Shah K,Barbosa-Morais NL,Harris N,Veiga-Fernandes H
14-0902 was used in Flow cytometry/Cell sorting to reveal that neuron-ILC2 cell units confer immediate tissue protection through coordinated neuroimmune sensory responses.
Thu Sep 14 00:00:00 EDT 2017
The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage.
Nature immunology
Shan Q,Zeng Z,Xing S,Li F,Hartwig SM,Gullicksrud JA,Kurup SP,Van Braeckel-Budimir N,Su Y,Martin MD,Varga SM,Taniuchi I,Harty JT,Peng W,Badovinac VP,Xue HH
14-0902 was used in Flow cytometry/Cell sorting to show that Runx3-mediated Tcf7 repression coordinately enforced acquisition of cytotoxic functions and protected the cytotoxic lineage integrity by preventing TFH-lineage deviation.
Tue Aug 01 00:00:00 EDT 2017
Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.
The Journal of clinical investigation
Zang S,Li J,Yang H,Zeng H,Han W,Zhang J,Lee M,Moczygemba M,Isgandarova S,Yang Y,Zhou Y,Rao A,You MJ,Sun D,Huang Y
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation.
The Journal of experimental medicine
Singh PB,Pua HH,Happ HC,Schneider C,von Moltke J,Locksley RM,Baumjohann D,Ansel KM
14-0902 was used in Flow cytometry/Cell sorting to establish the physiological requirements for miRNAs in ILC2 homeostasis and immune function ans compare the global miRNA repertoire of resting and activated ILC2s and T helper type 2 cells.
Mon Dec 04 00:00:00 EST 2017
A mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract.
Proceedings of the National Academy of Sciences of the United States of America
Oh JE,Oh DS,Jung HE,Lee HK
14090282 was used in flow cytometry to propose that type 2 immunity is induced by a unique mechanism in the genital tract
Tue Feb 14 00:00:00 EST 2017
A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice.
Haematologica
Cañete A,Carmona R,Ariza L,Sánchez MJ,Rojas A,Muñoz-Chápuli R
14090282 was used in flow cytometry to utilize a G2-Gata4Cre;R26REYFP mouse line to track the developmental fate of the G2-Gata4 cell lineage
Sat Apr 01 00:00:00 EDT 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
PLoS pathogens
Pyle CJ,Uwadiae FI,Swieboda DP,Harker JA
14-0902-82 was used in Flow Cytometry to show that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27.
Fri Sep 01 00:00:00 EDT 2017
HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival.
Cell death & disease
Lacher SM,Bruttger J,Kalt B,Berthelet J,Rajalingam K,Wörtge S,Waisman A
14-0902 was used in Flow cytometry/Cell sorting to show that protein prenylation rather than cholesterol biosynthesis pathway is indispensible for T-cell survival.
Thu May 25 00:00:00 EDT 2017
Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence.
Nature
Ibiza S,García-Cassani B,Ribeiro H,Carvalho T,Almeida L,Marques R,Misic AM,Bartow-McKenney C,Larson DM,Pavan WJ,Eberl G,Grice EA,Veiga-Fernandes H
14090282 was used in flow cytometry to explain how glial cells impact ILC3-derived IL-22
Thu Jul 21 00:00:00 EDT 2016
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Nature immunology
Monticelli LA,Buck MD,Flamar AL,Saenz SA,Tait Wojno ED,Yudanin NA,Osborne LC,Hepworth MR,Tran SV,Rodewald HR,Shah H,Cross JR,Diamond JM,Cantu E,Christie JD,Pearce EL,Artis D
14-0902 was used in Flow cytometry/Cell sorting to identify Arg1 as a key regulator of group 2 innate lymphoid cell bioenergetics that control proliferative capacity and pro-inflammatory functions.
Wed Jun 01 00:00:00 EDT 2016
Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.
Blood
Delemarre EM,van den Broek T,Mijnheer G,Meerding J,Wehrens EJ,Olek S,Boes M,van Herwijnen MJ,Broere F,van Royen A,Wulffraat NM,Prakken BJ,Spierings E,van Wijk F
14-0902 was used in Flow cytometry/Cell sorting to suggest Treg therapy may hamper development of long-term tolerance and should be approached with caution in the clinical autologous setting.
Thu Jan 07 00:00:00 EST 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis.
Mucosal immunology
Mohapatra A,Van Dyken SJ,Schneider C,Nussbaum JC,Liang HE,Locksley RM
14-0902 was used in Flow cytometry/Cell sorting to study how ILC2s link alveolar function to regulation of airway flow, revealing a key interaction between resident lymphoid and structural cells that might underlie similar organisational hierarchies in other organs.
Fri Jan 01 00:00:00 EST 2016
Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning.
Journal of immunology (Baltimore, Md. : 1950)
Müller AM,Florek M,Kohrt HE,Küpper NJ,Filatenkov A,Linderman JA,Hadeiba H,Negrin RS,Shizuru JA
14-0902 was used in Flow cytometry/Cell sorting to shed new light on the effects of CD4+ T cells on HSC biology.
Tue Nov 15 00:00:00 EST 2016
IL-6 Signaling in Myelomonocytic Cells Is Not Crucial for the Development of IMQ-Induced Psoriasis.
PloS one
Klebow S,Hahn M,Nikoalev A,Wunderlich FT,Hövelmeyer N,Karbach SH,Waisman A
14-0902 was used in Flow cytometry/Cell sorting to investigate the role of IL-6 signalling in myelomonocytic cells during experimental psoriasis.
Sun Jul 31 00:00:00 EDT 2016
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut.
Immunity
Kim MH,Taparowsky EJ,Kim CH
14090282 was used in flow cytometry and immunohistochemistry to discuss tissue tropisms of innate lymphoid cells
Tue Jul 21 00:00:00 EDT 2015
Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.
Mucosal immunology
Visekruna A,Linnerz T,Martinic V,Vachharajani N,Hartmann S,Harb H,Joeris T,Pfefferle PI,Hofer MJ,Steinhoff U
14-0902 was used in Flow cytometry/Cell sorting to investigate the role c-Rel plays in regulating innate lymphoid cells which induce anti-CD40-mediated innate colitis in mice.
Sun Mar 01 00:00:00 EST 2015
Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation.
PLoS pathogens
Sei JJ,Haskett S,Kaminsky LW,Lin E,Truckenmiller ME,Bellone CJ,Buller RM,Norbury CC
14-0902 was used in Flow cytometry/Cell sorting to suggest that direct antigen presentation is the dominant pathway in mice during mousepox.
Mon Jun 01 00:00:00 EDT 2015
Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Krishnamoorthy N,Burkett PR,Dalli J,Abdulnour RE,Colas R,Ramon S,Phipps RP,Petasis NA,Kuchroo VK,Serhan CN,Levy BD
14-0902 was used in Flow cytometry/Cell sorting to reveal that lung MaR1 augments de novo Treg generation, and that both Tregs and MaR1 inhibit ILC2s to restrain allergic lung inflammation.
Sun Feb 01 00:00:00 EST 2015
Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin.
Journal of immunology (Baltimore, Md. : 1950)
Grinberg-Bleyer Y,Dainichi T,Oh H,Heise N,Klein U,Schmid RM,Hayden MS,Ghosh S
14-0902-82 was used in Flow Cytometry to analyse the function of canonical NF-κB in the epidermis using CRE-mediated deletion of p65 and c-Rel in keratinocytes.
Sun Mar 15 00:00:00 EDT 2015
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.
Nature communications
Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Wed Jun 24 00:00:00 EDT 2015
Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.
Nature communications
Rouhani SJ,Eccles JD,Riccardi P,Peske JD,Tewalt EF,Cohen JN,Liblau R,Mäkinen T,Engelhard VH
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that when β-galactosidase (β-gal) is expressed in LECs, β-gal-specific CD8 T cells undergo deletion via the PD-1/PD-L1 and LAG-3/MHC-II pathways.
Fri Apr 10 00:00:00 EDT 2015
Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance.
Nature communications
Ozmadenci D,Féraud O,Markossian S,Kress E,Ducarouge B,Gibert B,Ge J,Durand I,Gadot N,Plateroti M,Bennaceur-Griscelli A,Scoazec JY,Gil J,Deng H,Bernet A,Mehlen P,Lavial F
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that Netrin-1 imbalance induces apoptosis mediated by the receptor DCC in a p53-independent manner.
Wed Jul 08 00:00:00 EDT 2015
Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance.
Nature communications
Ozmadenci D,Féraud O,Markossian S,Kress E,Ducarouge B,Gibert B,Ge J,Durand I,Gadot N,Plateroti M,Bennaceur-Griscelli A,Scoazec JY,Gil J,Deng H,Bernet A,Mehlen P,Lavial F
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that Netrin-1 imbalance induces apoptosis mediated by the receptor DCC in a p53-independent manner.
Wed Jul 08 00:00:00 EDT 2015
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
The Journal of clinical investigation
Kong G,Wunderlich M,Yang D,Ranheim EA,Young KH,Wang J,Chang YI,Du J,Liu Y,Tey SR,Zhang X,Juckett M,Mattison R,Damnernsawad A,Zhang J,Mulloy JC,Zhang J
14-0902 was used in Flow cytometry/Cell sorting to investigate the effect of combined targeting of MEK/ERK and JAK/STAT signalling on the murine myeloproliferative neoplasm.
Sun Jun 01 00:00:00 EDT 2014
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.
The Journal of clinical investigation
Moore-Morris T,Guimarães-Camboa N,Banerjee I,Zambon AC,Kisseleva T,Velayoudon A,Stallcup WB,Gu Y,Dalton ND,Cedenilla M,Gomez-Amaro R,Zhou B,Brenner DA,Peterson KL,Chen J,Evans SM
14-0902 was used in Flow cytometry/Cell sorting to study the the origins of cardiac fibroblasts during development and in fibrosis.
Tue Jul 01 00:00:00 EDT 2014
Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ΔureC::hly vaccine's superior protection against tuberculosis.
The Journal of infectious diseases
Vogelzang A,Perdomo C,Zedler U,Kuhlmann S,Hurwitz R,Gengenbacher M,Kaufmann SH
14-0902 was used in Flow cytometry/Cell sorting to investigate the T-cell population required for recombinant Bacillus Calmette-Guérin δureC::hly vaccine's enhanced protection against tuberculosis.
Mon Dec 15 00:00:00 EST 2014
Polymicrobial sepsis alters antigen-dependent and -independent memory CD8 T cell functions.
Journal of immunology (Baltimore, Md. : 1950)
Duong S,Condotta SA,Rai D,Martin MD,Griffith TS,Badovinac VP
14-0902 was used in Flow cytometry/Cell sorting to study the role of sepsis in shaping the quantity and functionality of infection- or vaccine-induced memory CD8 T cells.
Tue Apr 15 00:00:00 EDT 2014
Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.
PloS one
Thelemann C,Eren RO,Coutaz M,Brasseit J,Bouzourene H,Rosa M,Duval A,Lavanchy C,Mack V,Mueller C,Reith W,Acha-Orbea H
14-0902 was used in Flow cytometry/Cell sorting to investigate how epithelial MHCII expression is induced and how a deficiency in inducible epithelial MHCII expression alters susceptibility to colitis and the outcome of colon-specific immune responses.
Mon Dec 22 00:00:00 EST 2014
Renin-angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma.
Cell death & disease
Semba K,Namekata K,Guo X,Harada C,Harada T,Mitamura Y
14-0902 was used in Immunohistochemistry to identify the coupling of ER and CMA as a critical regulatory axis fundamental for physiological and pathological stress response.
Thu Jul 17 00:00:00 EDT 2014
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.
Nature immunology
Roediger B,Kyle R,Yip KH,Sumaria N,Guy TV,Kim BS,Mitchell AJ,Tay SS,Jain R,Forbes-Blom E,Chen X,Tong PL,Bolton HA,Artis D,Paul WE,Fazekas de St Groth B,Grimbaldeston MA,Le Gros G,Weninger W
14-0902 was used in Flow cytometry/Cell sorting to report the identification in normal mouse dermis of an abundant, phenotypically unique group 2 innate lymphoid cell subset that depended on interleukin 7 and constitutively produced IL-13.
Sat Jun 01 00:00:00 EDT 2013
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.
Nature immunology
Gracias DT,Stelekati E,Hope JL,Boesteanu AC,Doering TA,Norton J,Mueller YM,Fraietta JA,Wherry EJ,Turner M,Katsikis PD
14-0902 was used in Flow cytometry/Cell sorting to study the role of miR-155 in the regulation of CD8(+) T cell interferon responses to pathogens in vivo.
Sat Jun 01 00:00:00 EDT 2013
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.
The Journal of experimental medicine
Gao X,Johnson KD,Chang YI,Boyer ME,Dewey CN,Zhang J,Bresnick EH
14-0902 was used in Flow cytometry/Cell sorting to investigate the role of Gata2 cis-element in generation of hematopoietic stem cells.
Mon Dec 16 00:00:00 EST 2013
Aged mice exhibit a severely diminished CD8 T cell response following respiratory syncytial virus infection.
Journal of virology
Fulton RB,Weiss KA,Pewe LL,Harty JT,Varga SM
14-0902 was used in Flow cytometry/Cell sorting to investigate the extent to which CD8 T cell response to respiratory syncytial virus is altered with age, showing that age severely diminishes response.
Sun Dec 01 00:00:00 EST 2013
Cdc42 promotes host defenses against fatal infection.
Infection and immunity
Lee K,Boyd KL,Parekh DV,Kehl-Fie TE,Baldwin HS,Brakebusch C,Skaar EP,Boothby M,Zent R
14-0902 was used in Flow cytometry/Cell sorting to investigate the role of Cdc42-dependent signalling in fibroblasts, showing that it promotes host defences against fatal infection.
Thu Aug 01 00:00:00 EDT 2013
TGF-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation.
Nature immunology
Zhang N,Bevan MJ
14-0902 was used in Flow cytometry/Cell sorting to propose that TGF-β signaling controls the self-reactivity of peripheral T cells but that in the absence of TGF-β signals, an added trigger such as lymphopenia is needed to drive overt autoimmune disease.
Sun May 27 00:00:00 EDT 2012
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
Blood
Tewalt EF,Cohen JN,Rouhani SJ,Guidi CJ,Qiao H,Fahl SP,Conaway MR,Bender TP,Tung KS,Vella AT,Adler AJ,Chen L,Engelhard VH
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that LECs mediate deletion only via programmed cell death-1 (PD-1) ligand 1.
Thu Dec 06 00:00:00 EST 2012
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
Blood
Tewalt EF,Cohen JN,Rouhani SJ,Guidi CJ,Qiao H,Fahl SP,Conaway MR,Bender TP,Tung KS,Vella AT,Adler AJ,Chen L,Engelhard VH
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that LECs mediate deletion only via programmed cell death-1 (PD-1) ligand 1.
Thu Dec 06 00:00:00 EST 2012
Immunotherapy with IL-10- and IFN-γ-producing CD4 effector cells modulate "Natural" and "Inducible" CD4 TReg cell subpopulation levels: observations in four cases of patients with ovarian cancer.
Cancer immunology, immunotherapy : CII
Dobrzanski MJ,Rewers-Felkins KA,Samad KA,Quinlin IS,Phillips CA,Robinson W,Dobrzanski DJ,Wright SE
14-0902 was used in Flow cytometry/Cell sorting to study the use of IL-10- and IFN-γ-producing CD4 effector cells during immunotherapy in patients with ovarian cancer.
Fri Jun 01 00:00:00 EDT 2012
Population dynamics of naive and memory CD8 T cell responses after antigen stimulations in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Martin MD,Condotta SA,Harty JT,Badovinac VP
14-0902 was used in Flow cytometry/Cell sorting to investigate cell-autonomous functional differences between naive and memory CD8 T cells.
Wed Feb 01 00:00:00 EST 2012
Partial characterization of the Sox2+ cell population in an adult murine model of digit amputation.
Tissue engineering. Part A
Agrawal V,Siu BF,Chao H,Hirschi KK,Raborn E,Johnson SA,Tottey S,Hurley KB,Medberry CJ,Badylak SF
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2012
Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117.
PloS one
Saran N,Pommerencke J,Witzlau K,Regelin M,Krueger A
14-0902 was used in Flow cytometry/Cell sorting to suggest that a physiological thymic microenvironment does not optimally support T cell differentiation from triple negative precursors.
Mon Jun 18 00:00:00 EDT 2012
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
Mn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression.
Free radical biology & medicine
Li H,Wang Y,Pazhanisamy SK,Shao L,Batinic-Haberle I,Meng A,Zhou D
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that MnTE can mitigate TBI-induced long-term BM suppression by inhibiting IR-induced HSC senescence through the ROS-p16 pathway.
Fri Jul 01 00:00:00 EDT 2011
CD11b⁺, Ly6G⁺ cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection.
PLoS pathogens
Fischer MA,Davies ML,Reider IE,Heipertz EL,Epler MR,Sei JJ,Ingersoll MA,Rooijen NV,Randolph GJ,Norbury CC
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that innate immune effector cells contain a peripheral poxvirus infection, preventing systemic spread of the virus.
Tue Nov 01 00:00:00 EDT 2011
The generation of olfactory epithelial neurospheres in vitro predicts engraftment capacity following transplantation in vivo.
Experimental neurology
Krolewski RC,Jang W,Schwob JE
14-0902 was used in Immunocytochemistry-immunoflourescence to demonstrate that sphere formation serves as a biomarker for engraftment capacity and multipotency of olfactory progenitors.
Wed Jun 01 00:00:00 EDT 2011
T cell-intrinsic factors contribute to the differential ability of CD8+ T cells to rapidly secrete IFN-γ in the absence of antigen.
Journal of immunology (Baltimore, Md. : 1950)
Bou Ghanem EN,Nelson CC,D'Orazio SE
14-0902 was used in Flow cytometry/Cell sorting to demonstrate that the microenvironment in L. monocytogenes-infected BALB/c mice is sufficient to induce responsive CD8(+) T cells to rapidly secrete IFN-γ.
Tue Feb 01 00:00:00 EST 2011
Multiple CD4+ T cell subsets produce immunomodulatory IL-10 during respiratory syncytial virus infection.
Journal of immunology (Baltimore, Md. : 1950)
Weiss KA,Christiaansen AF,Fulton RB,Meyerholz DK,Varga SM
14-0902 was used in Flow cytometry/Cell sorting to evaluate the role of IL-10 in the modulation of the respiratory syncytial virus-specific immune response.
Thu Sep 15 00:00:00 EDT 2011
Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells.
PLoS pathogens
Wilson DC,Grotenbreg GM,Liu K,Zhao Y,Frickel EM,Gubbels MJ,Ploegh HL,Yap GS
14-0902 was used in Flow cytometry/Cell sorting to identify a novel H-2K(b)-restricted CTL population specific for the Toxoplasma antigen tgd057.
Fri Mar 19 00:00:00 EDT 2010
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Thu May 07 00:00:00 EDT 2009
Tracking epitope-specific T cells.
Nature protocols
Moon JJ,Chu HH,Hataye J,Pagán AJ,Pepper M,McLachlan JB,Zell T,Jenkins MK
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Tue Jun 30 00:00:00 EDT 2009
Critical roles of lysosomal acid lipase in T cell development and function.
The American journal of pathology
Qu P,Du H,Wilkes DS,Yan C
14-0902-82 was used in Flow Cytometry to conclude that the altered development and function of lal(-/-) T cells contributes to disease formation in various organs during LAL deficiency.
Sun Mar 01 00:00:00 EST 2009
Manganese superoxide dismutase gene dosage affects chromosomal instability and tumor onset in a mouse model of T cell lymphoma.
Free radical biology & medicine
van de Wetering CI,Coleman MC,Spitz DR,Smith BJ,Knudson CM
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 14-0902-82) in Flow Cytometry
Tue Apr 15 00:00:00 EDT 2008
