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            • Primary Antibodies ›
            • CCDC14 Antibodies

            Invitrogen

            CCDC14 Polyclonal Antibody

            1 Reference
            View all (4) CCDC14 antibodies
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            Cite CCDC14 Polyclonal Antibody

            • Antibody Testing Data (4)
            Application
            CCDC14 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 4

            CCDC14 Antibody (PA5-31759) in ICC/IF

            Immunocytochemistry-Immunofluorescence analysis of CCDC14 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: CCDC14 Polyclonal Antibody (Product # PA5-31759) diluted at 1:1000. Red: alpha Tubulin, a cytoskeleton marker. Blue: Hoechst 33342 staining.
            View Product

            CCDC14 Antibody in Immunocytochemistry (ICC/IF)
            CCDC14 Antibody in Immunocytochemistry (ICC/IF)
            CCDC14 Antibody in Western Blot (WB)
            CCDC14 Antibody in Western Blot (WB)

            Product Details

            PA5-31759

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:3,000
            -

            Immunocytochemistry (ICC/IF)

            1:100-1:1,000
            View 1 publication 1 publication
            Product Specifications

            Species Reactivity

            Human

            Published species

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein encompassing a sequence within the C-terminus region of human CCDC14. The exact sequence is proprietary.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7, with 1% BSA, 20% glycerol

            Contains

            0.01% thimerosal

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2549232

            Product Specific Information

            Recommended positive controls: 293T, A431, U87-MG, SK-N-SH, SK-N-AS.

            Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

            Target Information

            CCDC14 (Coiled-Coil Domain-Containing 14) is a gene that encodes a protein involved in ciliary function and cellular division processes. This protein contains coiled-coil domains that facilitate protein-protein interactions crucial for the assembly and stabilization of microtubule structures within the cell. Research indicates that CCDC14 is essential for proper ciliogenesis, the process by which cells form cilia, which are vital for cell motility, fluid movement, and signal transduction. Additionally, studies have revealed its significant role in the regulation of cell cycle progression and cytokinesis. CCDC14 is required for the accurate segregation of chromosomes during cell division, ensuring genomic stability. Mutations or dysregulation of CCDC14 can lead to ciliopathies and other cellular dysfunctions, highlighting its critical role in maintaining normal cellular activities and its potential implications in various diseases.

            ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Bioinformatics

            Protein Aliases: Coiled-coil domain-containing protein 14

            View more View less

            Gene Aliases: CCDC14

            View more View less

            UniProt ID: (Human) B8ZZ58

            View more View less

            Entrez Gene ID: (Human) 64770

            View more View less

            Function(s)

            protein binding

            Process(es)

            substantia nigra development protein localization to centrosome
            It has to be done as per old AB suggested Products section.
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