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            • Primary Antibodies ›
            • FBXL10 Antibodies

            Invitrogen

            FBXL10 Polyclonal Antibody

            View all (7) FBXL10 antibodies
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            Cite FBXL10 Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            FBXL10 Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            FBXL10 Antibody (PA5-41649) in WB

            Western blot analysis of human stomach cells using an anti-FBXL10 polyclonal antibody (Product # PA5-41649).
            View Product

            FBXL10 Antibody in Western Blot (WB)

            Product Details

            PA5-41649

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.2-1 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic peptide directed towards the middle region of human FBXL10

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.5 mg/mL

            Purification

            Affinity Chromatography

            Storage buffer

            PBS with 2% sucrose

            Contains

            0.09% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2606519

            Product Specific Information

            Peptide sequence: LSFFKRCGNI CHIDLRYCKQ VTKEGCEQFI AEMSVSVQFG QVEEKLLQKL

            Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

            Target Information

            This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: [Histone-H3]-lysine-36 demethylase 1B; CXXC-type zinc finger protein 2; F-box and leucine-rich repeat protein 10; F-box protein FBL10; F-box/LRR-repeat protein 10; JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein; JmjC domain-containing histone demethylation protein 1B; jumonji C domain-containing histone demethylase 1B; Jumonji domain-containing EMSY-interactor methyltransferase motif protein; lysine (K)-specific demethylase 2B; Lysine-specific demethylase 2B; Protein JEMMA; Protein-containing CXXC domain 2

            View more View less

            Gene Aliases: CXXC2; FBL10; FBXL10; JHDM1B; KDM2B; NDY1; PCCX2

            View more View less

            UniProt ID: (Human) Q8NHM5

            View more View less

            Entrez Gene ID: (Human) 84678

            View more View less

            Function(s)

            RNA polymerase II core promoter sequence-specific DNA binding DNA binding protein binding zinc ion binding rRNA binding histone demethylase activity histone demethylase activity (H3-K36 specific)

            Process(es)

            negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated spermatogenesis midbrain-hindbrain boundary morphogenesis fourth ventricle development lateral ventricle development third ventricle development initiation of neural tube closure positive regulation of cell growth forebrain development midbrain development hindbrain development histone H2A monoubiquitination negative regulation of neuron apoptotic process embryonic camera-type eye morphogenesis oxidation-reduction process histone H3-K36 demethylation positive regulation of stem cell population maintenance negative regulation of neural precursor cell proliferation
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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