Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute in 100 µL of MQ water. Centrifuge to remove any insoluble material.
The peptide shares 92% identity with mouse and rat sequences.
Specificity of this antibody: MRAP2.
Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MC2R accessory protein 2; Melanocortin-2 receptor accessory protein 2
Gene Aliases: bA51G5.2; BMIQ18; C6orf117; MRAP2
UniProt ID: (Human) Q96G30
Entrez Gene ID: (Human) 112609
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