High-resolution volumetric imaging and lamella preparation with the Hydra Bio Plasma-FIB

The Thermo Scientific Hydra Bio Plasma-FIB (PFIB) explores everything from tissues to proteins through volume electron microscopy—both at cryogenic and room temperatures—and through lamella preparation for cryo-tomography.

 

Great results start with sample preparation, so choose from four ion species (argon, nitrogen, oxygen, and xenon) that are compatible with all commonly used sample-embedding media and preparation protocols like high-pressure freezing and critical point drying to achieve the ultimate image.

 

The Hydra Bio Plasma-FIB addresses multiple workflows including high-resolution serial PFIB imaging, large-area serial PFIB imaging, array tomography, correlative light and electron microscopy, and high-throughput lamella preparation for cryo-tomography.

Get a closer look at Hydra Bio Plasma-FIB in our virtual webinar


Hydra Bio Plasma-FIB – advancing microscopy across sample types and workflows

Explore how the Hydra Bio Plasma-FIB can expand your research

Plasma-FIB for cryo and resin-embedded samples

Hydra Bio Plasma-FIB is versatile for volume electron microscopy and cellular cryo-tomography lamella preparation.

A versatile solution for multiple sample types

Explore tissues to proteins with the Hydra Bio Plasma-FIB with your sample in native condition (cryo) or resin-embedded.

One microscope, multiple workflows

Hydra Bio Plasma-FIB supports multiple workflows with specific software and accessories to complete your experiments.

Representative data showing iFLM correlative microscopy system combing fluorescent imaging with PFIB SEM

Plasma-FIB resources

Meet fellow scientists and reach resources to gain valuable insights into the latest trends and developments.

Mouse hippocampus visualized using PFIB SEM Spin Mill Bio method for large-area planar milling

Cryo-FIB for your lab

Choose the best cryo-focused-ion-beam (cryo-FIB) for your laboratory.  Learn more about other microscope models.

Thermo Scientific Arctis Cryo-Plasma FIB with representative tomography data

Explore volume electron microscopy

Volume EM is a group of techniques that reveals the 3D ultrastructure of cells and tissues at micron to millimeter volume scales, at nanometer-level resolutions.

Representative volume electron microscopy data
Header image courtesy of Tessa Burch-Smith, Kirk Czymmek and Lolita Rotkina, Donald Danforth Plant Science Center.

For Research Use Only. Not for use in diagnostic procedures.

1x1 image pixel for data collection 1x1 image pixel for data collection