High-resolution volumetric imaging and lamella preparation with the Hydra Bio Plasma-FIB

The Thermo Scientific Hydra Bio Plasma-FIB (PFIB) explores everything from tissues to proteins through volume electron microscopy—both at cryogenic and room temperatures—and through lamella preparation for cryo-tomography.

 

Great results start with sample preparation, so choose from four ion species (argon, nitrogen, oxygen, and xenon) that are compatible with all commonly used sample-embedding media and preparation protocols like high-pressure freezing and critical point drying to achieve the ultimate image.

 

The Hydra Bio Plasma-FIB addresses multiple workflows including high-resolution serial PFIB imaging, large-area serial PFIB imaging, array tomography, correlative light and electron microscopy, and high-throughput lamella preparation for cryo-tomography.

Get a closer look at Hydra Bio Plasma-FIB in our virtual webinar


Hydra Bio Plasma-FIB – advancing microscopy across sample types and workflows

Explore how the Hydra Bio Plasma-FIB can expand your research

Plasma-FIB for cryo and resin-embedded samples

Hydra Bio Plasma-FIB is versatile for volume electron microscopy and cellular cryo-tomography lamella preparation.

A versatile solution for multiple sample types

Explore tissues to proteins with the Hydra Bio Plasma-FIB with your sample in native condition (cryo) or resin-embedded.

One microscope, multiple workflows

Hydra Bio Plasma-FIB supports multiple workflows with specific software and accessories to complete your experiments.

Representative data showing iFLM correlative microscopy system combing fluorescent imaging with PFIB SEM

Plasma-FIB resources

Meet fellow scientists and reach resources to gain valuable insights into the latest trends and developments.

Mouse hippocampus visualized using PFIB SEM Spin Mill Bio method for large-area planar milling

Cryo-FIB for your lab

Choose the best cryo-focused-ion-beam (cryo-FIB) for your laboratory.  Learn more about other microscope models.

Thermo Scientific Arctis Cryo-Plasma FIB with representative tomography data

Explore volume electron microscopy

Volume EM is a group of techniques that reveals the 3D ultrastructure of cells and tissues at micron to millimeter volume scales, at nanometer-level resolutions.

Representative volume electron microscopy data
Header image courtesy of Tessa Burch-Smith, Kirk Czymmek and Lolita Rotkina, Donald Danforth Plant Science Center.

For Research Use Only. Not for use in diagnostic procedures.