Dynabeads Products Selection Guide | Thermo Fisher Scientific

Find the right Dynabeads for your research

Dynabeads magnetic beads are widely used for various applications such as cell and exosome isolation, T cell activation, protein purification, and nucleic acid separation. To ensure successful results, it is important to choose the appropriate Dynabeads magnetic beads for your research. This selection guide is designed to help you select the right beads based on you research needs. It considers factors such as sample type, target molecule, and downstream application to provide tailored recommendations. Start with the desired application and follow the easy step-by-step selection.

Please choose a category

Cell isolation
T Cell activation and expansion
Exosome isolation and detection
Virus enrichment
Protein isolation (His tag/IP)
Nucleic acid isolation
Surface activated beads
Streptavidin beads
Cell and protein isolation/IP (Secondary antibody-coated beads)

Species
- Human
- Mouse
Intended use
- Research use only
- Clinical research
Cell subtype

Species	Intended use	Cell subtype	Cat. No.	Recommended Product
Mouse	Research use only	Polyclonal T cell activation	11456D	Dynabeads Mouse T-Activator CD3/CD28 for T-Cell Expansion and Activation (0.4 ml)
Mouse	Research use only	Polyclonal T cell activation	11452D	Dynabeads Mouse T-Activator CD3/CD28 for T-Cell Expansion and Activation (2 ml)
Mouse	Research use only	Polyclonal T cell activation	11453D	Dynabeads Mouse T-Activator CD3/CD28 for T-Cell Expansion and Activation (5 x 2 ml)
Human	Research use only	Polyclonal T cell activation	11161D	Dynabeads Human T-Activator CD3/CD28 for T Cell Expansion and Activation (0.4 ml)
Human	Research use only	Polyclonal T cell activation	11131D	Dynabeads Human T-Activator CD3/CD28 for T Cell Expansion and Activation (2 ml)
Human	Research use only	Polyclonal T cell activation	11132D	Dynabeads Human T-Activator CD3/CD28 for T Cell Expansion and Activation (5 x 2 ml)
Human	Clinical research	Polyclonal T cell activation	40203D	CTS (Cell Therapy Systems) Dynabeads CD3/CD28
Human	Research use only	Antigen-specific T cell activation	11162D	Dynabeads Human T-Activator CD3/CD28/CD137 (0.4 ml)
Human	Research use only	Antigen-specific T cell activation	11163D	Dynabeads Human T-Activator CD3/CD28/CD137 (2 ml)
Human	Clinical research	Polyclonal T cell activation	11141D	Dynabeads Human T-Expander CD3/CD28
Human	Research use only	Activation of regulatory T cells	11129D	Dynabeads Human Treg Expander

Note: For cell isolation using biotinylated antibodies, please select Streptavidin beads above.

Species
- Human
- Mouse
Cell Type
Cell Subtype
Method of Isolation

Species	Cell type	Cell subtype	Method of isolation	Technology	Cat. No.	Recommended Product
Human	T cells	Pan T cells	Negative isolation/Untouched cells		11344D	Dynabeads Untouched Human T Cells Kit
Human	T cells	CD2	Depletion Positive isolation (no bead release)		11159D	Dynabeads CD2
Human	T cells	CD3	Depletion Positive isolation (no bead release)		11151D	DYNABEADS CD3
Human	T cells	CD3	Positive isolation (with bead release)	Flowcomp technology	11365D	Dynabeads FlowComp Human CD3 Kit (obtain Bead-free cells after isolation)
Human	T cells	CD4	Negative isolation/Untouched cells		11352D	Dynabeads Untouched Human CD4 T Cells Kit (2 ml)
Human	T cells	CD4	Negative isolation/Untouched cells		11346D	Dynabeads Untouched Human CD4 T Cells Kit (10 ml)
Human	T cells	CD4	Depletion Positive isolation (no bead release)		11145D	Dynabeads CD4
Human	T cells	CD4	Positive isolation (with bead release)	Flowcomp technology	11361D	Dynabeads FlowComp Human CD4 Kit (obtain Bead-free cells after isolation)
Human	T cells	CD4	Positive isolation (with bead release)	Detachabead technology	11331D	Dynabeads CD4 Positive Isolation Kit (obtain Antibody- and Bead-free cells after isolation)
Human	T cells	CD8	Negative isolation/Untouched cells		11348D	Dynabeads Untouched Human CD8 T Cells Kit
Human	T cells	CD8	Depletion Positive isolation (no bead release)		11147D	Dynabeads CD8
Human	T cells	CD8	Positive isolation (with bead release)	Detachabead technology	11333D	Dynabeads CD8 Positive Isolation Kit (obtain Antibody- and Bead-free cells after isolation)
Human	T cells	CD8	Positive isolation (with bead release)	Flowcomp technology	11362D	Dynabeads FlowComp Human CD8 Kit (obtain Bead-free cells after isolation)
Human	T cells	CD25	Depletion Positive isolation (no bead release)		11157D	Dynabeads CD25
Human	T cells	Tregs (CD4+ CD25+)	Positive isolation (with bead release)	Detachabead technology	11363D	Dynabeads Regulatory CD4+/CD25+ T Cell Kit (obtain Antibody- and Bead-free cells after isolation)
Human	B cells	Pan B cells	Negative isolation/Untouched cells		11351D	Dynabeads Untouched Human B Cells Kit
Human	B cells	CD19	Depletion Positive isolation (with bead release)		11143D	Dynabeads CD19 Pan B (obtain Antibody- and Bead-free cells after isolation if combined with 12506D)
Human	B cells	CD19	Positive isolation (with bead release)	Detachabead technology	12506D	DETACHaBEAD CD19 Kit (Release reagent used in combination with 11143D)
Human	NK cells	Untouched NK cells	Negative isolation/Untouched cells		11349D	Dynabeads Untouched Human NK Cells Kit
Human	Monocytes	CD14	Depletion Positive isolation (no bead release)		11149D	Dynabeads CD14
Human	Monocytes	CD14	Positive isolation (with bead release)	Flowcomp technology	11367D	Dynabeads FlowComp Human CD14 Kit (obtain Bead-free cells after isolation)
Human	Monocytes	Untouched Monocytes	Negative isolation/Untouched cells		11350D	Dynabeads Untouched Human Monocytes Kit
Human	Dendritic cells	Untouched DCs	Negative isolation/Untouched cells		11308D	Dynabeads Human DC Enrichment Kit
Human	Tumor cells	CD45	Depletion Positive isolation (no bead release)		11153D	Dynabeads CD45
Human	Tumor cells	EpCAM	Depletion Positive isolation (no bead release)		16102	Dynabeads Epithelial Enrich
Human	Tumor cells	EpCAM	Positive isolation (with bead release)	CELLection technology	16203	CELLection Epithelial Enrich Dynabeads (obtain Bead-free cells after isolation)
Human	Leukocytes	CD45	Depletion Positive isolation (no bead release)		11153D	Dynabeads CD45
Human	Granulocytes	CD15	Depletion Positive isolation (no bead release)		11137D	Dynabeads CD15
Human	Endothelial cells	CD31	Depletion Positive isolation (no bead release)		11155D	Dynabeads CD31 Endothelial Cell
Human	Stem cells	CD34	Positive isolation (with bead release)	Detachabead technology	11301D	Dynabeads CD34 Positive Isolation Kit (obtain Antibody- and Bead-free cells after isolation)
Mouse	T cells	Pan T cells	Negative isolation/Untouched cells		11413D	Dynabeads Untouched Mouse T Cells Kit
Mouse	T cells	Pan T cells	Depletion Positive isolation (no bead release)		11413D	Dynabeads Mouse Pan T (Thy1.2)
Mouse	T cells	Pan T cells	Positive isolation (with bead release)	Flowcomp technology	11465D	Dynabeads FlowComp Mouse Pan T (CD90.2) Kit (obtain Bead-free cells after isolation)
Mouse	T cells	CD4	Negative isolation/Untouched cells		11416D	Dynabeads Untouched Mouse CD4 Cells Kit (2 x 10 ml)
Mouse	T cells	CD4	Negative isolation/Untouched cells		11415D	Dynabeads Untouched Mouse CD4 Cells Kit (4 ml)
Mouse	T cells	CD4	Depletion Positive isolation (no bead release)		11445D	Dynabeads Mouse CD4
Mouse	T cells	CD4	Positive isolation (with bead release)	Flowcomp technology	11461D	Dynabeads FlowComp Mouse CD4 Kit (obtain Bead-free cells after isolation)
Mouse	T cells	CD8	Negative isolation/Untouched cells		11417D	Dynabeads Untouched Mouse CD8 Cells Kit
Mouse	T cells	CD8	Depletion Positive isolation (no bead release)		11447D	Dynabeads Mouse CD8 (Lyt 2)
Mouse	T cells	CD8	Positive isolation (with bead release)	Flowcomp technology	11462D	Dynabeads FlowComp Mouse CD8 Kit (obtain Bead-free cells after isolation)
Mouse	T cells	Tregs (CD4+ CD25+)	Positive isolation (with bead release)	Flowcomp technology	11463D	Dynabeads FlowComp Mouse CD4+CD25+ Treg Cells Kit (obtain Bead-free cells after isolation)
Mouse	B cells	CD43	Negative isolation/Untouched cells		11422D	Dynabeads Mouse CD43 (Untouched B Cells)
Mouse	B cells	B220	Depletion Positive isolation (no bead release)		11441D	Dynabeads Mouse Pan B (B220)
Mouse	Dendritic cells	Untouched DCs	Negative isolation/Untouched cells		11429D	Dynabeads Mouse DC (Dendritic Cell) Enrichment

Surface group
Bead size

Surface group	Bead size	Cat. No.	Recommended Product
Amine	2.8 µm, Hydrophilic (M-270)	14307D	Dynabeads M-270 Amine (2 ml)
Amine	2.8 µm, Hydrophilic (M-270)	14308D	Dynabeads M-270 Amine (10 ml)
Carboxyl	2.8 µm, Hydrophilic (M-270)	14305D	Dynabeads M-270 Carboxylic Acid (2 ml)
Carboxyl	2.8 µm, Hydrophilic (M-270)	14306D	Dynabeads M-270 Carboxylic Acid (10 ml)
Carboxyl	1 µm, Hydrophilic (MyOne C1)	65011	Dynabeads MyOne Carboxylic Acid (2 ml)
Carboxyl	1 µm, Hydrophilic (MyOne C1)	65012	Dynabeads MyOne Carboxylic Acid (10 ml)
Epoxy	2.8 µm, Hydrophilic (M-270)	14301	Dynabeads M-270 Epoxy (60 mg)
Epoxy	2.8 µm, Hydrophilic (M-270)	14302D	Dynabeads M-270 Epoxy (300 mg)
Epoxy	4.5 µm, Hydrophobic (M-450)	14011	Dynabeads M-450 Epoxy
Tosylactivated	2.8 µm, Hydrophobic (M-280)	14203	Dynabeads M-280 Tosylactivated (2 ml)
Tosylactivated	2.8 µm, Hydrophobic (M-280)	14204	Dynabeads M-280 Tosylactivated (10 ml)
Tosylactivated	4.5 µm, Hydrophobic (M-450)	14013	Dynabeads M-450 Tosylactivated
Tosylactivated	1 µm, Hydrophobic (MyOne T1)	65501	Dynabeads MyOne Tosylactivated (2 ml)
Tosylactivated	1 µm, Hydrophobic (MyOne T1)	65502	Dynabeads MyOne Tosylactivated (10 ml)

Note: For complete Exosome workflow products, please visit Exosome page.

Ligand type
Application

Ligand type	Application	Cat. No.	Recommended Product
CD9	Exosome isolation	10614D	Exosome-Human CD9 Isolation Reagent (from cell culture)
CD9	Exosome detection (by flow cytometry)	10620D	Exosome-Human CD9 Flow Detection Reagent (from cell culture)
CD63	Exosome isolation Exosome detection (by flow cytometry)	10606D	Exosome-Human CD63 Isolation/Detection Reagent (from cell culture media)
CD81	Exosome isolation	10616D	Exosome-Human CD81 Isolation Reagent (from cell culture)
CD81	Exosome detection (by flow cytometry)	10622D	Exosome-Human CD81 Flow Detection Reagent (from cell culture)
EpCAM	Exosome isolation	10618D	Exosome-Human EpCAM Isolation Reagent (from cell culture)
EpCAM	Exosome detection (by flow cytometry)	10624D	Exosome-Human EpCAM Flow Detection Reagent (from cell culture)
Protein A	Immunoprecipitation	10610D	Exosome Immunoprecipitation Reagent (Protein A)
Protein G	Immunoprecipitation	10612D	Exosome Immunoprecipitation Reagent (Protein G)
Streptavidin	Exosome isolation Exosome detection (by flow cytometry)	10608D	Exosome-Streptavidin Isolation/Detection Reagent

Enrichment method
- Precipitation reagent
- Magnetic beads

Enrichment method	Cat. No.	Recommended Product
Precipitation reagent	10720D	Intact Virus Precipitation Reagent (optimized for SARS-CoV-2)
Magnetic beads	10700D	Dynabeads Intact Virus Enrichment (optimized for SARS-CoV-2), 100 rxn
Magnetic beads	10701D	Dynabeads Intact Virus Enrichment (optimized for SARS-CoV-2), 500 rxn

Note: For Biotinylated Nucleic acid isolation, please select Streptavidin beads above.

Isolation type
- RNA isolation
- DNA isolation

Isolation type	Cat. No.	Recommended Product
RNA isolation	61002	Dynabeads Oligo(dT)25 (2 ml)
RNA isolation	61005	Dynabeads Oligo(dT)25 (5 ml)
RNA isolation	61021	Dynabeads mRNA DIRECT Micro Purification Kit
RNA isolation	61011	Dynabeads mRNA DIRECT Purification Kit (5 ml)
RNA isolation	61012	Dynabeads mRNA DIRECT Purification Kit (10 ml)
RNA isolation	61006	Dynabeads mRNA Purification Kit (for mRNA purification from total RNA preps)
DNA isolation	63102	Dynabeads DNA DIRECT Blood Kit
DNA isolation	63006	Dynabeads DNA DIRECT Universal Kit
DNA isolation	37012D	Dynabeads SILANE Genomic DNA Kit

Note: To identify the right bead size for your experiment, please refer to Dynabeads Streptavidin Trial Kit which contains 1 mL each of all the four bead types- M-270, M-280, MyOne C1 and MyOne T1.

Application
- Molecular applications
- Cellular applications
Bead size

Application	Bead size	Cat. No.	Recommended Product
Molecular applications	2.8 µm, Hydrophilic (M-270)	65305	Dynabeads M-270 Streptavidin (2 ml)
Molecular applications	2.8 µm, Hydrophilic (M-270)	65306	Dynabeads M-270 Streptavidin (10 ml)
Molecular applications	2.8 µm, Hydrophobic (M-280)	11205D	Dynabeads M-280 Streptavidin (2 ml)
Molecular applications	2.8 µm, Hydrophobic (M-280)	11206D	Dynabeads M-280 Streptavidin (10 ml)
Molecular applications	2.8 µm, Hydrophobic (M-280)	60210	Dynabeads M-280 Streptavidin (100 ml)
Molecular applications	2.8 µm, Hydrophobic (M-280)	60101	Dynabeads kilobaseBINDER Kit
Molecular applications	1 µm, Hydrophilic (MyOne C1)	65001	Dynabeads MyOne Streptavidin C1 (2 ml)
Molecular applications	1 µm, Hydrophilic (MyOne C1)	65002	Dynabeads MyOne Streptavidin C1 (10 ml)
Molecular applications	1 µm, Hydrophobic (MyOne T1)	65601	Dynabeads MyOne Streptavidin T1 (2 ml)
Molecular applications	1 µm, Hydrophobic (MyOne T1)	65602	Dynabeads MyOne Streptavidin T1 (10 ml)
Molecular applications	1 µm, Hydrophobic (MyOne T1)	65604D	Dynabeads MyOne Streptavidin T1 (50 ml)
Cellular applications	2.8 µm, Hydrophobic (M-280)	11047	Dynabeads Biotin Binder (Use any biotinylated antibody; No Bead release)
Cellular applications	2.8 µm, Hydrophobic (M-280)	11061D	Dynabeads FlowComp Flexi Kit (DSB-X biotinylate your antibody; With Bead release)
Cellular applications	4.5 µm, Hydrophilic (M-450)	11533D	CELLection Biotin Binder Kit (Use any biotinylated antibody; With Bead release)

Note: For Biotinylated Protein isolation, please select Streptavidin beads above.

Application
- His tag isolation/pulldown
- IP/Co-IP
Ligand type

Application	Ligand type	Cat. No.	Recommended Product
His tag isolation/pulldown	Cobalt-based chemistry	10103D	Dynabeads His-Tag Isolation and Pulldown (2 ml)
His tag isolation/pulldown	Cobalt-based chemistry	10104D	Dynabeads His-Tag Isolation and Pulldown (10 ml)
IP/Co-IP	Protein A	10001D	Dynabeads Protein A for Immunoprecipitation (1 ml)
IP/Co-IP	Protein A	10002D	Dynabeads Protein A for Immunoprecipitation (5 ml)
IP/Co-IP	Protein A	10008D	Dynabeads Protein A for Immunoprecipitation (50 ml)
IP/Co-IP	Protein A	10013D	Dynabeads Protein A and Magnet Starter Pack (40 reactions)
IP/Co-IP	Protein A	10016D	Dynabeads Protein A and Magnet Starter Pack (100 reactions)
IP/Co-IP	Protein G	10003D	Dynabeads Protein G for Immunoprecipitation (1 ml)
IP/Co-IP	Protein G	10004D	Dynabeads Protein G for Immunoprecipitation (5 ml)
IP/Co-IP	Protein G	10009D	Dynabeads Protein G for Immunoprecipitation (50 ml)
IP/Co-IP	Protein G	10014D	Dynabeads Protein G and Magnet Starter Pack (40 reactions)
IP/Co-IP	Protein G	10017D	Dynabeads Protein G and Magnet Starter Pack (100 reactions)
IP/Co-IP	Protein A and G	10015D	Dynabeads Protein A/Protein G and Magnet Starter Pack
IP/Co-IP	Protein A	10006D	Dynabeads Protein A Immunoprecipitation Kit
IP/Co-IP	Protein G	10007D	Dynabeads Protein G Immunoprecipitation Kit
IP/Co-IP	Protein A	10018D	Dynabeads Protein A IP Kit and Magnet Starter Pack
IP/Co-IP	Protein G	10019D	Dynabeads Protein G IP Kit and Magnet Starter Pack
IP/Co-IP	Any antibody (covalent binding)	14321D	Dynabeads Co-Immunoprecipitation Kit
IP/Co-IP	Any antibody (covalent binding)	14311D	Dynabeads Antibody Coupling Kit

Note: For Biotinylated Protein isolation, please select Streptavidin beads above.

Bead specificity
Method of isolation
- Cell isolation
- Protein isolation

Bead specificity	Method of isolation	Cat. No.	Recommended Product
Anti-rat IgGs	Cell isolation	11035	Dynabeads Sheep Anti-Rat IgG
Anti-mouse IgGs	Cell isolation	11041	Dynabeads Pan Mouse IgG (5 ml)
Anti-mouse IgGs	Cell isolation	11042	Dynabeads Pan Mouse IgG (5 x 5 ml)
Anti-mouse IgGs	Cell isolation	11531D	CELLection Pan Mouse IgG Kit
Anti-mouse IgG1, IgG2a and IgG2b	Cell isolation	11031	Dynabeads Sheep-Anti Mouse IgG
Anti-mouse IgG1, IgG2a and IgG2b	Protein isolation	11201D	Dynabeads M-280 Sheep Anti-Mouse IgG (2 ml)
Anti-mouse IgG1, IgG2a and IgG2b	Protein isolation	11202D	Dynabeads M-280 Sheep Anti-Mouse IgG (10 ml)
Anti-mouse IgGs	Cell isolation	11033	Dynabeads Goat Anti-Mouse IgG
Anti-mouse IgMs	Cell isolation	11039D	Dynabeads Rat Anti-Mouse IgM
Anti-rabbit IgGs	Protein isolation	11203D	Dynabeads M-280 Sheep Anti-Rabbit IgG (2 ml)
Anti-rabbit IgGs	Protein isolation	11204D	Dynabeads M-280 Sheep Anti-Rabbit IgG (10 ml)

Stylesheet for Classic Wide Template adjustments

For Research Use Only. Not for use in diagnostic procedures.