Name: Yohimbine hydrochloride, 99%
SKU: 141030050

Yohimbine hydrochloride, 99%

Element Search

Structure Search

Thermo Scientific Chemicals

Yohimbine hydrochloride, 99%

Yohimbine hydrochloride, CAS # 65-19-0, is an α2-adrenergic receptor antagonist, which blocks the central α2-adrenegic receptors in the brain.

Quantity:

5 g

Packaging:

Glass bottle

Try the chem dex^TM web app

Catalog number 141030050

Price (USD)/ Each

Quantity:

5 g

Packaging:

Glass bottle

Request bulk or custom format

Chemical Identifiers

CAS65-19-0

IUPAC Namehydrogen methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-2(10),4,6,8-tetraene-19-carboxylate chloride

Molecular FormulaC21H27ClN2O3

InChI KeyPIPZGJSEDRMUAW-VJDCAHTMSA-N

SMILES[H+].[Cl-].COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCC4=C(NC5=CC=CC=C45)[C@@H]3C[C@H]12

Specifications

Specification Sheet

Appearance (Color)White to light yellow

Appearance (Form)Powder

Infrared spectrumConforms

Titration with HClO4>=98.5 %

Specific optical rotation+99° to +105° (20°C, 589 nm) (c=1, H2O)

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Yohimbine hydrochloride is an indole alkaloid derived from the tree bark

• It is an antagonist of α2-adrenergic receptors in the brain, reducing the

effects of xylazine, which is an α2-adrenergic agonist

Applications

• Yohimbine hydrochloride blocks the central α2-adrenegic receptors in the brain

• It can reduce or eradicate effects of xylazine, which is an α2-adrenergic agonist

• It can have an antidiuretic effect

RUO – Research Use Only

General References:

Zhang, W. and Roomans, G.M. A yohimbine-dependent, UK14,304 induced ion transient in HT29 cells studied by X-ray microanalysis. Scanning microscopy, 1996, 10 (1), 293-299.
Susan, X. Jiang et. al. Reversible inhibition of intracellular calcium influx through NMDA receptors by imidazoline I2receptor antagonists. European Journal of Pharmacology. 2010, 629,(1), 12-19.