4-Pentyn-2-ol is used in Quantitative structure activity relationship (QSAR) studies pertaining to toxic levels of organic compounds in environmental situations. It is also used in the preparation of Fischer-type rhenium(III) benzoyldiazenido-2-oxacyclocarbenes. Further, it is used in the preparation of C-aryl glycosides by undergoing cycloaddition reaction with an aryl nitrile oxide.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Pentyn-2-ol is used in Quantitative structure activity relationship (QSAR) studies pertaining to toxic levels of organic compounds in environmental situations. It is also used in the preparation of Fischer-type rhenium(III) benzoyldiazenido-2-oxacyclocarbenes. Further, it is used in the preparation of C-aryl glycosides by undergoing cycloaddition reaction with an aryl nitrile oxide.
Solubility
Miscible with chloroform and ethyl acetate.
Notes
Incompatible with strong oxidizing agents, acid chlorides and acid anhydrides.
RUO – Research Use Only
General References:
- Di Franco, T.; Epenoy, A.; Hu, X. Synthesis of E-Alkyl Alkenes from Terminal Alkynes via Ni-Catalyzed Cross-Coupling of Alkyl Halides with B-Alkenyl-9-borabicyclo[3.3.1]nonanes. Org. Lett. 2015, 17 (19), 4910-4913.
- Wendler, E. P.; Santos, A. A. D. A general A3-coupling reaction based on functionalized alkynes. Quim. Nova 2013, 36 (8), 1155-1159.