Thermo Scientific Chemicals

2-Bromo-5-fluorobenzyl bromide, 97%, Thermo Scientific Chemicals

Catalog number: L09553.06
5 g, Each
Thermo Scientific Chemicals

2-Bromo-5-fluorobenzyl bromide, 97%, Thermo Scientific Chemicals

Catalog number: L09553.06
5 g, Each
Quantity
Catalog number: L09553.06
also known as L09553-06
Price (USD)

Chemical Identifiers

CAS
112399-50-5
IUPAC Name
1-bromo-2-(bromomethyl)-4-fluorobenzene
Molecular Formula
C7H5Br2F
InChI Key
CZLWYKAZAVYQIK-UHFFFAOYSA-N
SMILES
FC1=CC(CBr)=C(Br)C=C1
Appearance (Color)
Colorless to white to cream to pale brown
Form
Crystals or powder or crystalline powder or fused solid or clear liquid as melt
Melting Point (clear melt)
30.0-40.0?C
Assay (GC)
≥96.0%
Refractive Index
1.5870-1.5920 @ 20?C

Description

It is an important pharmaceutical intermediate. Alkylation of the β-amino ester 1a with 2-bromo-5-fluorobenzyl bromide yields Benzazepines as a white solid after silica gel chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is an important pharmaceutical intermediate. Alkylation of the β-amino ester 1a with 2-bromo-5-fluorobenzyl bromide yields Benzazepines as a white solid after silica gel chromatography.

Solubility
Difficult to mix in water.

Notes
Store in cool dry condition. Incompatible with strong oxidizing agents. Ensure ventilation. Protect from electrostatic charges.
RUO – Research Use Only

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