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MicroRNAs (miRNAs) are short, highly conserved small noncoding RNA molecules naturally occurring in the genomes of plants and animals. They are 17–27 nucleotides long and regulate posttranscriptional mRNA expression, typically by binding to the 3’ untranslated region (3’-UTR) of the complementary mRNA sequence, resulting in translational repression and gene silencing. Studies have shown that thousands of human protein-coding genes are regulated by miRNAs, indicating that miRNAs are “master regulators” of many important biological processes.
Novel design to minimize off-target effects | Next generation chemistries for lowest off-target effects | Chemically modified for good efficacy | Next generation chemistries for highest efficacy | |
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Order now | Order now | Order now | Order now | |
Pre-miR Precursors | mirVana miRNA Mimics | Anti-miR Inhibitors | mirVana miRNA Inhibitors | |
Function | Mimic endogenous miRNAs | Mimic endogenous miRNAs | Inhibit endogenous miRNAs | Inhibit endogenous miRNAs |
Content Database | 100% Coverage of miRBase v 15* | 100% Coverage of miRBase v 21** | 100% Coverage of miRBase v 15* | 100% Coverage of miRBase v 21** |
Model System | In Vitro | In Vitro & In Vivo | In Vitro | In Vitro & In Vivo |
Species Covered | Human, Mouse & Rat (Other species: use custom tool) | Human, Mouse & Rat (Other species: use custom tool) | Human, Mouse & Rat (Other species: use custom tool) | Human, Mouse & Rat (Other species: use custom tool) |
Custom Design Tool | Design your custom miRNAs mimics | Design your custom miRNAs mimics | Design your custom miRNA inhibitors | Design your custom miRNA inhibitors |
miRNA Libraries | Pre-Designed or Custom Libraries | Designed or Custom Libraries | Designed or Custom Libraries | Designed or Custom Libraries |
Recommended Catalog # | AM17100: Pre-miR miRNA Precursor 5 nM | 4464066: mirVana™ miRNA Mimic 5 nM | AM17000: Anti-miR Inhibitor 5 nM | 4464084: mirVana™ miRNA Inhibitor 5 nM |
miRNAs require special tools for accurate and sensitive analysis. We offer a broad portfolio of products that provides complete solutions for either miRNA expression profiling or a targeted quantitation/target validation.
miRNA Controls, Customs, & Libraries | miRNA & Small RNA Isolation | Real Time PCR Based miRNA Analysis | miRNA & Non-Coding RNA Microarrays |
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miRNA Experimental Planning & Design
Need help with your miRNA research? Contact us for a consultation and quote today.
If you have any questions on products or ordering, please contact us at RNAisupport@thermofisher.com
Our Learning Center provides an overview of epigenetic regulation of gene expression as well as considerations underpinning the research workflow. Learn about:
*This promotion is open to customers in Austria, Belgium, Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, Luxembourg, Netherlands, Norway, Poland, Portugal, South Africa, Spain, Slovakia, Sweden, Switzerland and the UK who purchase qualifying miRNA products. Discount will apply to qualifying orders received by Thermo Fisher Scientific no later than 31st March 2019. Discount applies to the list price in effect at the time the order is received by Thermo Fisher Scientific. Cannot be combined with other discounts or promotions. Offer void where prohibited, licensed, or restricted by federal, state, provincial, or local laws or regulation or agency/institutional policy. Other restrictions may apply.
For Research Use Only. Not for use in diagnostic procedures.
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