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Zitierungen und Referenzen (14)
Invitrogen™
Muscimol, BODIPY™ TMR-X Konjugat
Muscimol ist ein starker Agonist des GABAA -Rezeptors und wurde häufig zur reversiblen Inaktivierung lokalisierter Gruppen von Neuronen verwendet. DasWeitere Informationen
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| Katalognummer | Menge |
|---|---|
| M23400 | 1 mg |
Katalognummer M23400
Preis (EUR)
794,00
Each
Vorrätig
Menge:
1 mg
Preis (EUR)
794,00
Each
Muscimol ist ein starker Agonist des GABAA -Rezeptors und wurde häufig zur reversiblen Inaktivierung lokalisierter Gruppen von Neuronen verwendet. Das BODIPY TMR-X Muscimol-Konjugatkann anstelle radioaktiver Reagenzien und Methoden verwendet werden, um die Verteilung von Muscimol im Nervensystem abzubilden und um das Vorhandensein von GABAA-Rezeptoren auf Zelloberflächen zu erkennen.
Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.
Specifications
NachweisverfahrenFluoreszenz
Anregung/Emission543/572 nm
Zur Verwendung mit (Geräte)Fluoreszenzmikroskop
SummenformelC31H36BF2N5O5.
Molekulargewicht607.46
ProduktlinieBODIPY™
Menge1 mg
Empfohlene LagerungIm Tiefkühlgerät (-5 °C bis -30 °C) lagern und vor Licht schützen.
VersandbedingungRaumtemperatur
FarbeGelb
Physikalische FormFest
ProdukttypMuscimol
Unit SizeEach
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Zertifikate
Nach Chargennummer oder Teil-Chargennummer suchen
Chargen-Nr.Certificate TypeDateCatalog Number(s)
3163181Certificate of Analysis22. Apr. 2025M23400
2935427Certificate of Analysis12. Aug. 2024M23400
2647608Certificate of Analysis26. Juli 2023M23400
2403710Certificate of Analysis25. Okt. 2021M23400
2291482Certificate of Analysis28. Jan. 2021M23400
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Sicherheitsdatenblätter
SDBHandbuch Molecular Probes®
Zitierungen und Referenzen (14)
Search citations by name, author, journal title or abstract text
Zitierungen und Referenzen
Abstract
Activation of membrane receptors by a neurotransmitter conjugate designed for surface attachment.
Journal:Biomaterials
PubMed ID:15576163
'The derivatization of surfaces with bioactive molecules is a research area of growing importance for cell and tissue engineering. Tetherable molecules used in such applications must contain an anchoring moiety as well as the biofunctional group, typically along with a spacer to prevent steric clashes between the target molecule and
Activity-dependent neurotransmitter-receptor matching at the neuromuscular junction.
Journal:Proc Natl Acad Sci U S A
PubMed ID:17190810
'Signaling in the nervous system requires matching of neurotransmitter receptors with cognate neurotransmitters at synapses. The vertebrate neuromuscular junction is the best studied cholinergic synapse, but the mechanisms by which acetylcholine is matched with acetylcholine receptors are not fully understood. Because alterations in neuronal calcium spike activity alter transmitter specification
Imaging the spread of reversible brain inactivations using fluorescent muscimol.
Journal:J Neurosci Methods
PubMed ID:18377997
Muscimol is a GABA A-agonist that causes rapid and reversible suppression of neurophysiological activity. Interpretations of the effects of muscimol infusions into the brain have been limited because of uncertainty about spread of the drug around the injection site. To solve this problem, the present study explored the use of
GABA(A) receptor binding and localization in the tiger salamander retina.
Journal:Vis Neurosci
PubMed ID:10750823
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the retina and also appears to act as a trophic factor regulating photoreceptor development and regeneration. Although the tiger salamander is a major model system for the study of retinal circuitry and regeneration, our understanding of GABA receptors in this species
A cross-modality enhancement of defensive flight via parvalbumin neurons in zona incerta.
Journal:Elife
PubMed ID:30985276
14 total citations