Knockout™ Serum Replacement (Knockout™ SR) is for serum-free, feeder-based culture of embryonic stem cells (ESCs) and induced Pluripotent stem cells (iPSCs) from multiple species. This defined, serum-free formulation directly replaces FBS in existing protocols.
Many of the drawbacks of using FBS in stem cell culture, (differentiation of cells and heat-inactivation) can be alleviated with the use of KnockOut™ Serum Replacement. ES and iPS cells grown in KnockOut™ SR-supplemented media are substantially less differentiated than those grown in FBS-supplemented media, and germline transmission should not be compromised. With over 2000 peer-reviewed publications covering applications such as stem cell culture, differentiation, iPSC generation, ESC derivation, and transgenic modeling, KnockOut™ Serum Replacement is widely cited for stem cell culture.
Specifications
Classification
Serum-Free
Culture Type
Mammalian Cell Culture
Cell Type
Stem Cells (Embryonic)
Species
Serum-Free
Form
Frozen
Serum Level
Serum-Free
Product Type
Serum Replacement
Quantity
100 mL
Tested For
Growth Performance Assay
Manufacturing Quality
cGMP for medical devices, 21 CFR Part 820 and ISO 13485
For Use With (Application)
Clinical Research, Translational Research
Green Features
Sustainable packaging
Purity or Quality Grade
ES Cell-Qualified
Product Line
KnockOut™
pH
6 to 8
Shelf Life
18 Months
Shipping Condition
Dry Ice
Contents & Storage
Store in freezer (-5 to -20°C) and protect from light.