CaptureSelect™ Human Albumin Affinity Matrix
CaptureSelect™ Human Albumin Affinity Matrix
Thermo Scientific™

CaptureSelect™ Human Albumin Affinity Matrix

Thermo Scientific™ CaptureSelect™ Human Albumin Affinity Matrix has been specifically designed for the purification of human albumin and albumin fusion proteins.
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Catalog NumberQuantity
19129701L1 L
1912970055 mL
19129701010 mL
19129705050 mL
1912970250250 mL
19129705L5 L
Catalog number 19129701L
Price (KRW)
-
Quantity:
1 L
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CaptureSelect Human Albumin Affinity Matrix has been specifically designed for the purification of human albumin and albumin fusion proteins.

Features of this affinity matrix include:

  • Highly selective for human albumin
  • Unique elution characteristics allowing for gentle elution of albumin fusion proteins
  • Excellent scalability
  • Non-animal-derived

The high selectivity and yields obtained using CaptureSelect Human Albumin Affinity Matrix enable a robust and efficient purification process with excellent purity obtained in one step. The mild elution conditions make the resin suitable for the purification of albumin fusion proteins, especially those that are pH sensitive.

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main Characteristics:

  • Matrix: agarose-based, aldehyde-activated
  • Average particle size: 65 ± 10 μm
  • Ligand: CaptureSelect HSA affinity ligand
  • Ligand coupling method: aldehyde coupling via NH2 residues of the ligand
  • Binding capacity: ∼15 mg albumin/mL resin
  • Elution conditions (neutral pH): 20 mM Tris, pH 7.4 with 2 M MgCl2 or with 1 M NaCl + 50%(v/v) propylene glycol or with 1 M NaCl + 0.5 M L-arginine
  • Elution conditions (acidic pH): 0.1 M glycine, pH 3.0
  • Flow characteristics: 50–200 cm/h (up to 2 bar)
  • Formulation buffer: 20%(v/v) ethanol
Specifications
Binding Capacity∼15 mg albumin/mL resin
Flow Rate50 to 200 cm/hr. (Up to 2 bar)
Ligand TypeHSA affinity ligand
MatrixAgarose-based, aldehyde-activated
Quantity1 L
Stationary PhaseAnti-HSA
FormLiquid Suspension
Particle Size65 ±10 μm
Product LineCaptureSelect™
TypeAffinity Matrix
Unit SizeEach
Contents & Storage
Store in refrigerator (2° to 8°C).
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Certificates

Lot #Certificate TypeDateCatalog Number(s)
J000239Certificate of AnalysisDec 13, 20231912970250
210524-01Certificate of AnalysisJun 26, 20231912970250
FA2312Certificate of AnalysisJun 12, 20231912970250
J000011Certificate of AnalysisMay 01, 20231912970250
FA2264Certificate of AnalysisSep 13, 20221912970250
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Limited Use Label Licenses (LULL)

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Notice to Purchaser: The purchase of this product conveys to the purchaser the limited, non-transferable right to use the purchased amount of the product, under intellectual property rights that are owned and/or controlled by Life Technologies and relate specifically to the product, to perform (a) internal research for the sole benefit of the purchaser; (b) quality control testing conducted by the purchaser on a fee for service or contract basis for or on behalf of third parties; and (c) performance of research or manufacturing services conducted by the purchaser on a fee for service or contract basis for or on behalf of third parties. The purchase of this product does not grant the purchaser any additional rights, including, without limitation, the right to transfer or resell the product in any form, the right to use the product as a therapeutic agent or diagnostics test component, or to use the product to perform tests other than what is indicated in this Limited Use Label License on a contract or fee per test basis for or on behalf of third parties. For information on obtaining additional rights, please contact outlicensing@thermofisher.com, Licensing and Commercial Supply, Thermo Fisher Scientific, 5823 Newton Drive, Carlsbad, CA, 92008, United States.

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